Ubiquitin-specific protease 15 contributes to gastric cancer progression by regulating the Wnt/β-catenin signaling pathway

Table 1 Ubiquitin-specific protease 15 expression and clinicopathological characteristics of gastric cancer patients

Parameters	n	USP15 expression
		low	High	P value
Gender
Male	62	20	42	0.218
Female	53	23	30
Age in year
≤ 60	53	18	35	0.482
> 60	62	25	37
Differentiation
Poor	69	25	44	0.753
Moderate/well	46	18	28
Tumor size in cm
≤ 4	66	32	34	0.004
> 4	49	11	38
TNM stage
I + II	58	28	30	0.015
III + IV	57	15	42
Depth of invasion
T1 + T2	54	27	27	0.009
T3 + T4	61	16	45
LNI
N0	43	24	19	0.002
N1 + N2+N3	72	19	53
Perineural invasion
No	51	25	26	0.021
Yes	64	18	46
Vascular invasion
No	50	27	23	0.001
Yes	65	16	49
Total	115	43	72

GC: Gastric cancer; LNI: Lymph node involvement; TNM: Tumor-node-metastasis; USP15: Ubiquitin-specific protease 15.