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©The Author(s) 2020.
World J Gastroenterol. Feb 28, 2020; 26(8): 865-876
Published online Feb 28, 2020. doi: 10.3748/wjg.v26.i8.865
Published online Feb 28, 2020. doi: 10.3748/wjg.v26.i8.865
Ref. | Country | Study type | Sample size | Key findings | |
LSG | LRYGB | ||||
Du et al[1], 2017 | China | Randomized clinical trial | 19 | 74 | Overall remission rate achieved with LRYGB and LSG was 75.9% at 1 yr and 56.4% at 3 yr |
Safety profile, T2DM resolution and other morbid obesity-related comorbidities by both procedures are comparable | |||||
Garg et al[42], 2017 | India | Retrospective clinical | 40 | 40 | The median duration of T2DM was higher in LRYGB than LSG (2.2 vs 1.8), respectively |
Both LRYGB and LSG showed significant but similar improvement in T2DM remission | |||||
Park and Kim[43], 2015 | South Korea | Retrospective Cohort Study | 104 | 236 | The study found comparable results with insignificant differences between LRYGB and LSG |
Perrone et al[27], 2016 | Italy | Prospective clinical trials | 162 | 142 | LSG is more effective in obese men than in women for excess weight loss. However, there is no difference in terms of the remission of comorbidities |
LRYGB showed similar findings in both genders for excess weight loss and comorbidity resolution, including T2DM | |||||
Perrone et al[44], 2017 | Italy | Prospective clinical trial | 162 | 142 | LRYGB showed better T2DM resolution rate in the short-term |
Neither LRYGB nor LSG showed a significant difference in T2DM remission in the long-term | |||||
Praveenraj et al[14], 2016 | India | Retrospective clinical trial | 54 | 32 | LRYGB showed better surgical outcomes than LSG in patients > 50 yr |
LSG had shorter operative times and shorter hospital stays | |||||
Peterli et al[45], 2018 | Finland | The SLEEVEPASS multicenter, randomized clinical trial | 120 | 120 | Complete or partial remission of T2DM was reported in 37% after LSG and in 45% LRYGB. No significant difference in terms of T2DM resolution is reported between LRYGB and LSG |
Wallenius et al[29], 2018 | Sweden | Prospective clinical trial | 15 | 18 | There was a similar decrease in post-op fasting blood glucose in both the LRYGB and LSG groups |
LRYGB and LSG showed similar outcomes in glycemic control, with insignificant differences in short- and mid-term follow-up | |||||
Yang et al[22], 2015 | China | Randomized clinical study | 22 | 23 | LSG and LRYGB had comparable effects on T2DM remission in the Chinese study cohort with a BMI of 28-35 kg/m2 |
- Citation: Guraya SY, Strate T. Surgical outcome of laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass for resolution of type 2 diabetes mellitus: A systematic review and meta-analysis. World J Gastroenterol 2020; 26(8): 865-876
- URL: https://www.wjgnet.com/1007-9327/full/v26/i8/865.htm
- DOI: https://dx.doi.org/10.3748/wjg.v26.i8.865