Prevalence and associated factors of obesity in inflammatory bowel disease: A case-control study

Table 1 Baseline demographic and disease characteristics of inflammatory bowel disease population

Parameter	mean ± SD or n (%)
Age (yr)	46.2 ± 13.2
Sex
Male	474 (58.7)
Female	333 (41.3)
Smokers	132 (16.4)
BMI (kg/m2)	24.5 ± 5.0
CD	438 (54.2)
UC	369 (45.8)
IBD age onset	20.0 ± 9.4
HBI	1.3 ± 2.4
CD behavior
Inflammatory B1	237 (54.1)
Stricturing B2	128 (29.2)
Penetrating B3	60 (16.7)
CD extension
L1 Ileal	198 (45.2)
L2 colic	44 (10.0)
L3 ileocolic	164 (37.4)
Perianal	3 (0.68)
L4 upper GI	16 (3.6)
UC extension
Proctitis E1	164 (44.4)
Left colitis E2	55 (14.9)
Pancolitis E3	123 (40.7)
Mayo Score	1.7 ± 1
CD previous surgery	109 (24.9)
Colectomy for UC	30 (8.1)
Azathioprine	300 (37.2)
Systemic corticosteroids
< 3 courses/yr	471 (58.4)
> 3 courses/yr	101 (12.5)
Topical corticosteroids
In course	94 (11.6)
Previously taken	190 (23.5)
Infliximab	147 (18.2)
Adalimumab	131 (16.2)
Golimumab	28 (3.5)
Vedolizumab	35 (4.3)
Antibiotics	451 (55.9)
Diabetes	39 (4.8)
Hypertension	79 (9.8)
Waist circumference (> 102 cm males, > 88 females)	138 (17.1)
Liver steatosis	232 (28.7)

BMI: Body mass index; UC: Ulcerative colitis; CD: Crohn’s disease; IBD: Inflammatory bowel disease; HBI: Harvey-Bradshaw index; SD: Standard deviation; GI: Gastrointestinal.

Table 2 Main characteristics of inflammatory bowel disease patients and controls

Variable	IBD (n = 807)	Controls (n = 378)	P value
Age	46.2 ± 13.2	45.9 ± 17.7	0.66
Male sex	474 (58.7%)	210 (55.5%)	0.30
BMI	24.5 ± 5.0	24.4 ± 4.4	0.74
Obesity	56 (6.9%)	30 (7.9%)	0.38
Diabetes	39 (4.8%)	14 (3.7%)	0.77
Smokers	132 (16.4%)	90 (23.8%)	0.002
Hypertension	79 (9.8%)	82 (21.7%)	< 0.001
Abdominal circumference > 102 in males, > 88 in females	138 (17.1%)	76 (20.1%)	0.21

BMI: Body mass index; IBD: Inflammatory bowel disease.