Retrospective Study
Copyright ©The Author(s) 2017.
World J Gastroenterol. Dec 28, 2017; 23(48): 8553-8561
Published online Dec 28, 2017. doi: 10.3748/wjg.v23.i48.8553
Table 1 Clinical characteristics of patients who underwent laparoscopic-assisted total gastrectomy and totally laparoscopic total gastrectomy
VariableLATG, n = 266TLTG, n = 421P value
Age in years, mean ± SD55.69 ± 11.9657.78 ± 11.200.020
Sex0.583
Male167 (62.8)273 (64.8)
Female99 (37.2)148 (35.2)
ASA score0.064
I181 (68.0)249 (59.1)
II68 (25.6)145 (34.4)
III17 (6.4)27 (6.4)
BMI in kg/m20.883
< 23119 (44.7)198 (47.0)
≥ 23, < 2570 (26.3)103 (24.5)
≥ 25, < 3069 (25.9)110 (26.1)
≥ 308 (3.0)10 (2.4)
History of abdominal surgery33 (12.4)85 (20.2)0.008
Table 2 Pathologic results of the laparoscopic-assisted total gastrectomy and totally laparoscopic total gastrectomy groups
VariableLATG, n = 266TLTG, n = 421P value
Tumor size in cm3.72 ± 2.473.95 ± 2.900.302
Retrieved lymph nodes, n34.91 ± 13.9240.04 ± 15.59< 0.001
metastatic lymph nodes, n0.63 ± 2.590.82 ± 3.200.421
Proximal margin in cm3.85 ± 3.112.68 ± 2.62< 0.001
Distal margin in cm12.72 ± 4.8612.79 ± 4.670.870
TNM (AJCC/UICC) staging0.395
IA202 (75.9)285 (67.7)
IB26 (9.8)52 (12.4)
IIA19 (7.1)40 (9.5)
IIB8 (3.0)22 (5.2)
IIIA5 (1.9)8 (1.9)
IIIB4 (1.5)11 (2.6)
IIIC2 (0.8)3 (0.7)
Table 3 Early surgical outcomes in patients undergoing laparoscopic-assisted total gastrectomy and totally laparoscopic total gastrectomy
VariablesLATG, n = 266TLTG, n = 421P value
Operation time in min170 (65-453)149 (75-342)< 0.001
Hematocrit change in (%)4.04 (-3.8-15.2)3.49 (-4.9-18.6)0.002
Intra-operative transfusion1 (0.4)1 (0.2)1.000
Post operative transfusion28 (10.5)55 (13.1)0.32
Intra-operative event27 (10.2)13 (3.1)< 0.001
Intra-operative anastomosis event19 (7.1)10 (2.4)0.003
Combined operation17 (6.4)27 (6.4)1.000
Time to first flatus in d (range)3.60 (1-7)3.30 (1-7)< 0.001
Time to soft diet in d (range)4.61 (2-68)4.30 (3-36)< 0.001
Pick of pain score, score (range)7.11 (2-10)6.96 (3-10)0.912
8AM Pain socre of POD #1, score (range)3.45 (0-10)3.49 (0-10)0.841
8AM Pain socre of POD #3, score (range)2.44 (0-9)2.54 (0-7)0.529
8AM Pain socre of POD #5, score (range)1.75 (0-10)1.51 (0-8)0.055
Number of administration of analgesics, n (range)2.49 (0-69)2.86 (0-67)0.131
Post-operative hospital stay in d (range)7.02 (5-1117)6.75 (4-82)0.005
Table 4 Early and late postoperative complications n (%)
Early complications
Late complications
LATG, n = 266TLTG, n = 421P valueLATG, n = 266TLTG, n = 421P value
CDC0.4470.681
0213 (80.1)334 (79.3)245 (92.1)384 (91.2)
124 (9.0)26 (6.2)10 (3.8)15 (3.6)
213 (4.9)26 (6.2)0 (0)4 (1.0)
312 (4.5)33 (7.8)11 (4.1)18 (4.3)
44 (1.5)2 (0.5)0 (0)0 (0)
Cx of EJ0.2110.439
None252 (94.7)407 (96.7)262 (98.5)418 (99.3)
Leakage14 (5.3)14 (3.3)1 (0.4)1 (0.2)
Stricture0 (0.0)0 (0.0)3 (1.1)2 (0.5)
Table 5 Postoperative complications in patients who underwent laparoscopic-assisted total gastrectomy and totally laparoscopic total gastrectomy n (%)
LATG, n = 266TLTG, n = 421
Bleeding4 (1.50)8 (1.90)
EJ leakage15 (5.64)15 (3.56)
EJ stricture3 (1.13)2 (0.48)
Intraabdominal fluid collection8 (3.01)26 (6.18)
Internal hernia5 (1.88)12 (2.85)
Mechanical ileus10 (3.76)28 (6.65)
Paralytic ileus3 (1.13)7 (1.66)
Wound infection18 (6.77)9 (2.14)
Other surgical complications4 (1.50)8 (1.90)
Medical complications4 (1.50)2 (0.48)