Luo XL, Xie DX, Wu JX, Wu AD, Ge ZQ, Li HJ, Hu JB, Cao ZX, Gong JP. Detection of metastatic cancer cells in mesentery of colorectal cancer patients. World J Gastroenterol 2017; 23(34): 6315-6320 [PMID: 28974898 DOI: 10.3748/wjg.v23.i34.6315]
Corresponding Author of This Article
Jian-Ping Gong, MD, PhD, Tongji Cancer Research Institute, Department of Gastrointestinal Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Av., Wuhan 430030, Hubei Province, China. jpgong@tjh.tjmu.edu.cn
Research Domain of This Article
Surgery
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Sep 14, 2017; 23(34): 6315-6320 Published online Sep 14, 2017. doi: 10.3748/wjg.v23.i34.6315
Table 1 Data in 63 colorectal cancer patients
Parameters
Results
Gender
Female
25
Male
38
Age (yr, mean, range)
55.5 (28-86)
Location of cancer
Colon
11
Rectum
52
Differentiated grade
Well
6
Moderately
46
Poorly
11
Affected lymph nodes
N0
35
N1
14
N2
14
Invasive depth
T1
1
T2
12
T3
39
T4
11
Table 2 Data in Metastasis V-positive patients
Patients
Sex
Age (yr)
Cancer size (cm)
Cancer location
Differentiated grade
Invasive depth
Affected lymph nodes
TNM
1
F
37
2.5
Rectum
Poorly
Serosal
8/15
pT4N2M0
2
F
42
3
Rectum
Moderately
Subserosal
5/17
pT3N2M0
3
M
33
2
Rectum
Moderately
Serosal
5/15
pT4N2M0
4
M
48
6
Sigmoid
Well
Serosal
12/21
pT4N2M0
5
F
63
3
Rectum
Poorly
Muscularis
0/15
pT2N2M0
6
F
45
3
Rectum
Moderately
Serosal
5/28
pT4N2M0
7
M
58
3
Rectum
Poorly
Subserosal
8/12
pT3N2M0
8
M
64
4
Rectum
Poorly
Subserosal
7/15
pT3N2M1
9
M
54
6
Rectum
Moderately
Subserosal
2/13
pT3N1M0
10
F
60
2
Descending colon
Moderately
Subserosal
0/17
pT3NxM0
11
M
54
3
Rectum
Moderately
Serosal
5/12
pT4N2M0
12
M
58
3
Rectum
Moderately
Subserosal
0/16
pT3N0M0
13
F
57
3
Rectum
Poorly
Serosal
2/21
pT4N1M1
14
M
47
4
Rectum
Moderately
Subserosal
24/32
pT3N2M0
Table 3 Comparison between Metastasis V-positive patients and Metastasis V- negative patients
Parameters
Metastasis V
P value
Negative
Positive
Age (yr)
NS
< 45
8
3
≥ 45 and ≤ 59
19
8
≥ 60
22
3
Cancer size (cm)
NS
≤ 3
24
10
> 3 and < 5
14
2
≥ 5
11
2
Gender
NS
Female
19
6
Male
30
8
Cancer location
NS
Colon
9
2
Rectum
40
12
Differentiated grade
NS
Well
5
1
Moderately
38
8
Poorly
6
5
Affected lymph nodes
< 0.05
N0
32
3
N1
12
2
N2
5
9
Invasive depth
< 0.05
T1
1
0
T2
11
1
T3
32
7
T4
5
6
Table 4 Comparison of preoperative CEA levels between Metastasis V-positive and Metastasis V-negative patients
Parameters
Metastasis V
P value
Negative
Positive
Median (ng/mL)
3
4.27
< 0.05
Grade
< 0.05
High (> 15.00 ng/mL)
5
5
Low (≤ 15.00 ng/mL)
73
16
Citation: Luo XL, Xie DX, Wu JX, Wu AD, Ge ZQ, Li HJ, Hu JB, Cao ZX, Gong JP. Detection of metastatic cancer cells in mesentery of colorectal cancer patients. World J Gastroenterol 2017; 23(34): 6315-6320