©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 14, 2017; 23(34): 6315-6320
Published online Sep 14, 2017. doi: 10.3748/wjg.v23.i34.6315
Published online Sep 14, 2017. doi: 10.3748/wjg.v23.i34.6315
Detection of metastatic cancer cells in mesentery of colorectal cancer patients
Xue-Lai Luo, Da-Xing Xie, Jian-Xin Wu, An-Ding Wu, Zong-Qing Ge, Hai-Jie Li, Jun-Bo Hu, Zhi-Xin Cao, Jian-Ping Gong, Tongji Cancer Research Institute, Department of Gastrointestinal Surgery, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China
Author contributions: Luo XL and Xie DX contributed equally to this work; Gong JP conceived and designed the study; Luo XL, Wu JX, Wu AD and Ge ZQ contributed to data acquisition, data analysis and interpretation; Luo XL and Xie DX wrote the article; Li HJ, Hu JB and Cao ZX revised and reviewed the article; all authors have reviewed and approved the final manuscript.
Supported by the National Natural Science Foundation of China , No. 81572861, No. 81302309 and No. 81372324 .
Institutional review board statement: All procedures performed in the study were in accordance with the ethical standards of Tongji Hospital Ethics Committee, Wuhan, China.
Informed consent statement: Informed consent was obtained from all participants included in the study.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: No additional data are available.
Correspondence to: Jian-Ping Gong, MD, PhD, Tongji Cancer Research Institute, Department of Gastrointestinal Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Av., Wuhan 430030, Hubei Province, China. jpgong@tjh.tjmu.edu.cn
Telephone: +86-27-83665275 Fax: +86-27-83662696
Received: November 2, 2016
Peer-review started: November 4, 2016
First decision: January 19, 2017
Revised: March 21, 2017
Accepted: May 19, 2017
Article in press: May 19, 2017
Published online: September 14, 2017
Processing time: 315 Days and 8.3 Hours
Peer-review started: November 4, 2016
First decision: January 19, 2017
Revised: March 21, 2017
Accepted: May 19, 2017
Article in press: May 19, 2017
Published online: September 14, 2017
Processing time: 315 Days and 8.3 Hours
Core Tip
Core tip: Local-regional recurrence of colorectal cancer (CRC) is common in patients who received R0 resection. Our previous study proposed a novel type of metastasis designated as “Metastasis V” in gastric cancer. Metastasis V is defined as the appearance of cancer cells in the mesentery in broad sense, and may be a risk factor for the poor prognosis after radical surgery. In this study, Metastasis V was also detected in the mesentery of colorectum, and it might be associated with the poor prognosis of CRC patients.