Comparison of short- and long-term outcomes of laparoscopic vs open resection for gastric gastrointestinal stromal tumors

Table 1 Baseline characteristics of laparoscopic resection and open resection groups before and after propensity score matching

Characteristics	Before PSM			After PSM
	LR group (n = 102)	OR group (n = 122)	P value	LR group (n = 80)	OR group (n = 80)	P value
Age, yr
> 60	45	54	0.983	39	35	0.526
≤ 60	57	68		41	45
Sex
Male	43	53	0.846	36	33	0.632
Female	59	69		44	47
BMI , kg/m2
< 28	92	110	0.994	75	72	0.385
≥ 28	10	12		5	8
ASA score
I	57	73	0.825	43	48	0.722
II	40	43		32	28
III	5	6		5	4
Tumor location
Proximal	61	49	0.014	47	36	0.141
Body	31	56		24	36
Antropyloric	10	17		9	8
Tumor size, cm
≤ 5	83	71	0.001	61	57	0.633
5-10	17	40		17	19
> 10	2	11		2	4
Surgical procedure
Wedge resection	96	89	0.000	74	69	0.200
Gastrectomy	6	33		6	11
Mitotic count
≤ 5	84	83	0.002	62	59	0.090
6-10	5	26		5	13
> 10	13	13		13	8
Risk stratification
Very low	34	9	0.000	15	9	0.485
Low	37	42		34	37
Intermediate	16	39		16	21
High	15	32		15	13

LR: Laparoscopic resection; OR: Open resection; PSM: Propensity score matching.

Table 2 Comparison of intraoperative and postoperative outcomes between laparoscopic resection and open resection groups after propensity score matching

Characteristics	LR group (n = 80)	OR group (n = 80)	t/χ2	P value
Operative time (min)	90.83 ± 37.69	118.38 ± 42.74	4.325	0.000
Intraoperative blood loss (mL)	91.88 ± 65.82	121.25 ± 103.05	2.149	0.033
Perioperative blood transfusion
No	79	77	1.026	0.620
Yes	1	3
Time to first flatus (d)	2.63 ± 0.62	3.01 ± 0.46	4.459	0.000
Time to oral intake (d)	3.86 ± 1.17	5.24 ± 5.04	2.377	0.019
Length of hospital stay (d)	9.26 ± 3.89	11.73 ± 9.34	2.176	0.031
Complications1
No	95% (76/80)	88.75% (71/80)	2.093	0.247
Yes	5% (4/80)	11.25% (9/80)

¹Postoperative complications were classified according to the Clavien-Dindo classification. LR: Laparoscopic resection; OR: Open resection; PSM: Propensity score matching.

Table 3 Comparison of long-term oncological outcomes between laparoscopic resection and open resection groups after propensity score matching

Characteristics	LR group (n = 80)	OR group (n = 80)	t/χ2	P value
Adjuvant therapy
No	58	61	0.295	0.587
Yes	22	19
Follow-up time (mo)	35.3 ± 26.02	40.99 ± 25.07	1.408	0.161
Recurrence
No	77	76	0.149	0.699
Yes	3	4
Death
No	79	78	0.340	0.560
Yes	1	2
DFS time (mo)1	97.04 ± 2.81	111.61 ± 5.12	0.023	0.880
5-yr DFS rate (%)2	97.5 (78/80)	96.25 (77/80)		1.000
OS time (mo)1	99.65 ± 2.30	115.26 ± 4.59	0.081	0.776
5-yr OS rate (%)2	98.75 (79/80)	98.75 (79/80)		1.000

¹Log-rank test;

²Fisher’s exact test. LR: Laparoscopic resection; OR: Open resection; PSM: Propensity score matching; DFS: Disease-free survival; OS: Overall survival.