Estimation of quality of life in Cypriot patients with inflammatory bowel disease

Table 1 Demographic and disease characteristics of the study population n (%)

	Total	CD	UC	P value
	n = 100	n = 40	n = 60
Sex				0.198
Male	54 (53.5)	61.5%	48.3%
Female	46 (46.5)	38.5%	51.7%
Age (yr) (n = 97)		n = 38	n = 59
18-35	39 (39.8)	16 (41.0)	23 (39.0)	0.979
35-50	28 (28.6)	11 (28.2)	17 (28.8)
> 51	30 (31.6)	11 (30.8)	19 (32.2)
Smoking	32 (33.0)	43.2%	26.7%	0.092
Education				0.673
Primary or less	17.3%	18.4%	16.7%
Secondary	49.0%	42.1%	53.3%
Tertiary or above	33.7%	39.5%	30.0%
Employment status				0.349
Government officials	19.8%	22.9%	18.3%
Private employee	44.8%	44.4%	45.0%
Self–employed	4.2%	8.3%	1.7%
Unemployed	31.3%	25.0%	35.0%
Family status				0.822
Married	62.6%	59.0%	65.0%
Unmarried	32.3%	35.9%	30.0%
Divorced	5.1%	5.1%	5.0%
Surgery	20.9%	36.1%	11.7%	0.004
Mean disease duration (yr)	12.63%	10.28%	14.07%	0.118
Treatment				0.019
Immunosuppressive treatment	65.0%	55.0%	71.7%
Immunosuppressive treatment + corticosteroids	16.0%	12.5%	18.3%
Treatment with biologic agents	19.0%	32.5%	10.0%
Treatment with corticosteroids	22.0%	17.5%	25.0%	0.375%

CD: Crohn’s disease; UC: Ulcerative colitis.

Table 2 Short inflammatory bowel disease questionnaire score by dimension and type of disease (n = 100), mean (± SD) n (%)

	Crohn’s disease	Ulcerative colitis
Physical dimension	18.53 (7.55)	19.52 (6.74)
Psychological dimension	10.68 (5.31)	11.88 (4.49)
Social dimension	7.92 (3.03)	8.63 (3.18)
Overall SIBDQ	33.79 (13.36)	36.30 (11.39)

SIBDQ: Short inflammatory bowel disease questionnaire.

Table 3 Physical Dimension scores of health-related quality of life in patients with Crohn’s disease and ulcerative colitis and their association to demographic parameters

	Physical dimension
	Crohn’s disease, median	Ulcerative colitis, median
Gender
Male	3.3	4.2
Female	3.5	3.4
Z	-0.015	-2.274
P value	0.988	0.023
Age
< 35	3.1	4.0
35-50	3.8	3.2
> 50	3.8	4.2
χ2	1.232	7.767
P value	0.540	0.021

Table 4 Psychological dimension scores of health-related quality of life in patients with Crohn’s disease and ulcerative colitis and their association to demographic parameters

	Psychological dimension
	Crohn’s disease, median	Ulcerative colitis, median
Gender
Male	3.17	5.00
Female	2.83	3.00
Z	-0.456	-3.474
P value	0.648	0.001
Age
< 35	2.83	4.00
35-50	2.33	2.67
> 51	4.67	4.67
χ2	1.011	5.979
P value	0.603	0.0503
Family status
Married	3.83	4.00
Single	2.33	3.50
Z	6.351	-0.663
P value	0.042	0.507

HRQoL: Health-related quality of life.

Table 5 Scores of health-related quality of life in patients with Crohn’s disease and ulcerative colitis in association to medication treatment

	Medication	Median	Z	P value
Physical dimension	Biological factors	5.00	-1.484	0.138
	Standard treatment	3.20
Psychological dimension	Biological factors	4.67	-1.584	0.113
	Standard treatment	2.67
Social dimension	Biological factors	5.00	-2.004	0.045
	Standard treatment	3.25

HRQoL: Health-related quality of life.