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Copyright ©The Author(s) 2015.
World J Gastroenterol. Oct 14, 2015; 21(38): 10830-10839
Published online Oct 14, 2015. doi: 10.3748/wjg.v21.i38.10830
Table 1 Comparison of surgical outcomes between laparoscopic Heller myotomy vs laparoscopic myotomy with fundoplication
AuthorYearStudy designSamplesProcedureFollow up (mo)SuccessPostop-GERD
Campos et al[36]2009Meta-analysis579myotomy onlyNA90%31%
2507myotomy + fundoplicationNA90%9%
Falkenback et al[37]2003RCT10myotomy only9670%13%
10myotomy + fundoplication9670%0.1%
Richards et al[10]2004RCT21myotomy only6100%47.6%
22myotomy + fundoplication695.5%9.1%
Simić et al[38]2010RCT22myotomy only36100%9.1%
62myotomy + fundoplication3691.7%9.7%
Finley et al[39]2007Retrospective24myotomy only12100%NA
71myotomy + fundoplication1298.6%NA
Table 2 Comparison of surgical outcomes between laparoscopic Heller myotomy with Dor fundoplication vs laparoscopic myotomy with other fundoplication
AuthorYearStudy designSamplesFundoplicationFollow up (mo)SuccessPostop-GERD
Rebecchi et al[40]2008RCT71Dor12597%3%
67Nissen12585%0%
Rawlings et al[41]2012RCT36Dor691.7%27.8%
24Toupet695.8%16.7%
Wright et al[42]2007Retrospective52Dor4682.7%NA
63Toupet4595.2%NA
Di Martino et al[43]2011Retrospective30Dor2493.4%13.3%
26Nissen2492.3%0%
Table 3 Comparison of surgical outcomes between laparoscopic Heller myotomy with fundoplication vs pneumatic dilation
AuthorYearStudy designSamplesApproachProcedureFollow up (mo)Successpostop-GERD
Kostic et al[56]2007RCT25laparoscopymyotomy + fundoplication12NANA
26endoscopypneumatic dilation12NANA
Novais et al[57]2010RCT47laparoscopymyotomy + fundoplication388.3%4.7%
47endoscopypneumatic dilation373.8%31%
Boeckxstaens et al[58]2011RCT106laparoscopymyotomy + fundoplication4390%23%
95endoscopypneumatic dilation4386%15%
Persson et al[59]2014RCT25laparoscopymyotomy + fundoplication6092%NA
28endoscopypneumatic dilation6064%NA
Table 4 Comparison of surgical outcomes between laparoscopic Heller myotomy vs peroral endoscopic myotomy n (%)
AuthorYearStudy designSamplesProcedureFollow up (d)OP time (min)Major complication (perforation)Postop-GERD
Hungness et al[66]2013Retrospective55myotomy421251 (2)NA
18POEM421131 (6)7 (39)
Ujiki et al[67]2013Case control21myotomy164154.51 (4.8)4 (19)
18POEM116155.81 (5.6)5 (27.8)
Table 5 Surgical outcomes of reoperation for patients with achalasia
AuthorYearSamplesApproach (primary)Approach (re-do)Mucosal injuryRe-revisionSatisfaction
Iqbal et al[71]20061510: Laparoscopy15: Laparoscopy30%20%40%-89%
3: Thoracoscopy(2: Conversion to laparotomy)
1: Laparotomy
1: Thoracotomy
Rakita et al[73]20071211: LaparoscopyNA25%82%
1: Thoracoscopy
Grotenhuis et al[74]20071913: Abdominal13: Abdominal15.8%10.5%50%
6: Thoracic6: Thoracic
Loviscek et al[75]20134320: Abdominal26: Laparoscopy4.7%9.3%79%
23: Thoracic
Omura et al[76]2012107: Laparoscopy5: Laparoscopy30%NA90%
3: Thoracoscopy2: Thoracoscopy
1: Laparotomy
1: Laparotomy + thoracotomy
Table 6 Surgical outcomes of reduced port surgery for patients with achalasia
AuthorYearSamplesProcedureFollow up (mo)OP time (min)Mucosal injuryConversion to laparotomySatisfaction
Barry et al[81]201166Myotomy + anterior fundoplicationNA1173%0%94%
Omura et al[82]Epub24Myotomy + anterior fundoplication823013%0%90%