Expression of renal Oat5 and NaDC1 transporters in rats with acute biliary obstruction

Table 1 Plasma total and direct bilirubin levels of Sham and BDL rats

	Sham	BDL
	(n = 4)	(n = 4)
Total bilirubin (mg/L)	5.1 ± 0.4	43.6 ± 2.8a
Direct bilirubin (mg/L)	2.2 ± 0.3	34.4 ± 3.3a

Results are expressed as means ± SE.

^aP < 0.05 vs Sham.

Table 2 Urine flow, creatinine clearance, urinary levels of glucose and protein, alkaline phosphatase urinary activity, urinary citrate concentration, urinary citrate excretion and urinary proton excretion of Sham and BDL rats

	Sham	BDL
	(n = 4)	(n = 4)
Urine flow (μL/min per 100 g bw)	2.10 ± 0.24	3.87 ± 0.57a
Creatinine clearance (mL/min per 100 g bw)	0.65 ± 0.03	0.53 ± 0.06
Glucose (g/g creatinine)	0.17 ± 0.10	0.17 ± 0.07
Protein (g/g creatinine)	1.15 ± 0.08	1.15 ± 0.10
Alkaline phosphatase (U/g creatinine)	266 ± 14	253 ± 20
Citrate concentration (g/L)	0.71 ± 0.16	0.07 ± 0.03a
Citrate excretion (g/g creatinine)	0.53 ± 0.11	0.07 ± 0.02a
Proton excretion (μmol/g creatinine)	0.082 ± 0.03	0.21 ± 0.04a

Results are expressed as means ± SE.

^aP < 0.05 vs Sham. bw: Body weight.