Impact of body mass index on complications following pancreatectomy: Ten-year experience at National Cancer Center in China

Table 1 Demographic, comorbidity, and operation type in patients grouped according to body mass index

Variable	BMI < 24 kg/m2 (n = 206)	BMI ≥ 24 kg/m2 (n = 156)	Total (n = 362)	P value
Mean age (yr)	59.32	63.14	60.97	0.0111
Sex
Male	95	84	179
Female	111	72	183
Male/female ratio	0.9	1.2	1.0	0.1452
Mean BMI (kg/m2)	21.075	26.993	23.625	< 0.0001
Smoking				0.3641
Never	135	95	230
Ever	71	61	132
Smoking amount (packs/yr)	51	57	53	0.3166
Mean smoking time (yr)	23.25	26.94	25.00	0.3558
Alcohol, n				0.6835
Never	166	123	289
Ever	40	33	73
Comorbidity, n
Any comorbidity	76	107	183	< 0.0001
Diabetes	38	43	81	0.0610
Coronary artery disease	9	40	49	< 0.0001
Hypertension	43	41	84	0.8930
COPD	6	6	12	0.6232
HBV	12	5	17	0.2198
HCV	5	2	7	0.4201
Previous history of cancer, n	1	2	3	0.4253
Previous abdominal surgery, n	21	16	37	0.9514
Family history of cancer, n	11	38	49	< 0.0001
Operation type, n
Pancreaticoduodenectomy	116	79	195	0.2839
Distal pancreatectomy	75	67	142	0.2069
Middle-segment pancreatectomy	15	10	25	0.7461

COPD: Chronic obstructive pulmonary disease; HBV: Hepatitis B virus; HCV: Hepatitis C virus; BMI: Body mass index.

Table 2 Postoperative complications in patients grouped according to body mass index n (%)

Complication	BMI < 24 kg/m2	BMI ≥ 24 kg/m2	Total	OR	95%CI	P value
	(n = 206)	(n = 156)	(n = 362)
Patients with any complication	61 (29.6)	67 (42.9)	128 (35.4)	1.128	1.087-1.376	0.0086
Pancreatic fistula	34 (16.5)	30 (19.2)	64 (17.7)	0.825	0.430-1.582	0.4340
Delayed gastric emptying	12 (5.8)	31 (19.9)	43 (11.9)	1.279	1.072-1.487	< 0.0001
Bile leak	4 (1.9)	12 (7.7)	16 (4.4)	1.332	1.193-1.725	0.0068
Reoperation	4 (1.9)	2 (1.3)	6 (1.7)	1.513	0.267-8.570	0.6627
Readmission	1 (0.5)	1 (0.6)	2 (0.6)	0.382	0.291-0.532	0.3897
Gastrointestinal hemorrhage	6 (2.9)	4 (2.6)	10 (2.8)	1.271	0.344-4.697	0.8782
Wound infection	8 (3.9)	8 (5.1)	16 (4.4)	0.513	0.193-1.367	0.2229
Cholangitis	3 (1.5)	2 (1.3)	5 (1.4)	1.162	0.253-3.921	0.8881
Urinary tract infection	8 (3.9)	10 (6.4)	18 (5.0)	0.469	0.212-1.219	0.2229
Pneumonia	2 (1.0)	3 (1.9)	5 (1.4)	1.143	0.893-2.134	0.4421
Intra-abdominal abscess	6 (2.9)	3 (1.9)	9 (2.5)	0.450	0.112-5.321	0.5493
Bacteremia	3 (1.5)	6 (3.8)	9 (2.5)	0.631	0.461-5.235	0.1481
Central line infection	7 (3.4)	6 (3.8)	13 (3.6)	0.778	0.353-2.341	0.8205
Pulmonary embolus	0 (0.0)	0 (0.0)	0 (0.0)	NA	NA	NA
Deep venous thrombosis	1 (0.5)	1 (0.6)	2 (0.6)	0.124	0.064-7.320	0.8432
Arrhythmia	7 (3.4)	7 (4.5)	14 (3.9)	0.491	0.212-1.625	0.5467
Cerebrovascular accident	1 (0.5)	0 (0.0)	1 (0.3)	NA	NA	0.3919
Mortality	3 (1.5)	2 (1.3)	5 (1.4)	1.259	0.203-7.815	0.9288

NA: Not applicable; BMI: Body mass index.

Table 3 Association between operative difficulty, length of hospital stay, and cost with body mass index

Variable	BMI < 24 kg/m2	BMI ≥ 24 kg/m2	Total	OR	95%CI	P value
	(n = 206)	(n = 156)	(n = 362)
Mean operative time (min)	229.59	235.03	231.91	0.942	0.651-1.362	0.6050
Mean intraoperative blood loss (mL)	450	520.41	481.16	0.926	0.617-1.389	0.4433
Blood transfusion, n	103	79	182	0.703	0.413-1.197	0.9311
Mean hospital stay (d)	21.85	24.22	22.87	0.968	0.670-1.398	0.1167
Mean cost (in RMB)	78519.62	76160.05	77527.28	1.493	0.760-2.931	0.8532

RMB: Renminbi.