Rectal tone and compliance affected in patients with fecal incontinence after fistulotomy

Table 1 Demographic data and etiology of fistula

Case	Age	Gender	Etiology	Type
1	38	Male	Idiopathic (perianal abscess)	Simple
2	34	Male	Idiopathic (perianal abscess)	Simple
3	67	Female	Idiopathic (perianal abscess)	Simple
4	50	Male	Idiopathic (abscess)	Complex
5	39	Male	Idiopathic (abscess)	Simple
6	45	Female	Idiopathic (abscess)	Complex
7	42	Female	Iatrogenic (miotomy)	Simple
8	47	Female	Iatrogenic (surgery)	Simple
9	48	Male	Idiopathic (abscess)	Simple
10	47	Male	Idiopathic (inter-sphincteric abscess)	Complex
11	41	Female	Idiopathic (inter-sphincteric abscess)	Complex

Table 2 Physiological data

	Fecal incontinence after Fistulotomy	Idiopathic fecal incontinence	Healthy subjects	P value
	(n = 11)	(n = 11)	(n = 11)	FIAF vs IFI	FIAF vs HS	IFI vs HS
Barostat
IOP (mmHg)	8.7 ± 1.6	7.9 ± 0.1a	9.6 ± 2.1	0.106	0.282	0.012
Tone (bag volume, mL)	42.6 ± 27.7a	63.6 ± 34.1a	103.5 ± 51.1	0.129	0.002	0.047
Compliance (v/p)	5 ± 3.4a	8.1 ± 4.3	11.8 ± 6.9	0.075	0.009	0.151
Rectal capacity (mL)	314.7 ± 76.1	332.6 ± 97.1	302.9 ± 82.3	0.636	0.735	0.460
First sensation (mmHg)	15.8 ± 3.1	16.6 ± 4.2	14.1 ± 5	0.627	0.336	0.220
Gas sensation (mmHg)	22 ± 3	20.5 ± 3.6	18 ± 6	0.381	0.107	0.292
Urge defecate (mmHg)	28.1 ± 6.6	30.5 ± 10.9	22.5 ± 7.2	0.600	0.107	0.069
Pain sensation (mmHg)	36.8 ± 7.2	34.1 ± 8.4	35.9 ± 8.8	0.480	0.818	0.656
Anorectal manometry data
Anal resting pressure (mmHg)	41.7 ± 24.3	44.2 ± 18.2	34.9 ± 22.9	0.791	0.506	0.306
Anal squeeze pressure (mmHg)	94.1 ± 88.8	109.9 ± 88.9a	43.2 ± 24.9	0.680	0.082	0.026
Spontaneous RAIR frequency (#)	1.9 ± 2.8	1.5 ± 1.5	1.4 ± 1.6	0.641	0.583	0.893
Induced RAIR relaxation (%)	66.3 ± 20.5	63.4 ± 16.7	74.4 ± 31.6	0.721	0.483	0.319
Induced RAIR duration (s)	18.4 ± 6.7	22.3 ± 6.5	19.8 ± 5.9	0.186	0.610	0.367

^aP < 0.05 vs healthy subjects. All data represent the mean ± SD. FIAF: Fecal incontinence after Fistulotomy; IFI: Idiopathic fecal incontinence; HS: Healthy subjects; RAIR: Rectoanal inhibitory reflex; IOP: Individual operating pressure.