ADV36 adipogenic adenovirus in human liver disease

Table 1 Multiple linear regressions to body mass index and homeostasis model assessment

	r	r2	r2change	F	Sig	β	P-value
BMI	0.667	0.445	0.445	17.842	< 0.0001
Waist/hip ratio						-0.013	0.841
FM,%						0.105	0.084
Total cholesterol, mg/dL						0.148	0.039
HDL cholesterol, mg/dL						-0.088	0.259
Triglycerides, mg/dL						-0.103	0.184
HOMA						0.564	< 0.0001
ADV36 seropositivity						0.182	0.004
HOMA	0.671	0.451	0.451	18.285	< 0.0001
Waist/hip ratio						-0.055	0.389
BMI, kg/m2						0.558	< 0.0001
FM, %						-0.032	0.598
Total cholesterol, mg/dL						0.004	0.956
HDL cholesterol, mg/dL						-0.102	0.188
Triglycerides, mg/dL						0.213	0.006
ADV36 seropositivity						0.005	0.938

Weighted least squares regression - weighted by age. Bold font indicates significant correlations. BMI: Body mass index; FM: Fat mass; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; ADV: Adenoviruses; HOMA: Homeostasis model assessment.

Table 2 Multiple Linear regression to non-alcoholic fatty liver disease-ADV37 seropositivity

	NAFLD
	r	r2	F	Sig	β	P-value
	0.632	0.4	18.789	< 0.0001
ADV37 seropositivity					0.222	0.001
HDL cholesterol, mg/dL					0.097	0.190
Triglycerides, mg/dL					0.133	0.073
HOMA					-0.052	0.572
BMI, kg/m2					-0.557	< 0.0001

Bold font indicates significant correlations. BLS: Bright liver score; HDL: High-density lipoprotein; BMI: Body mass index; NAFLD: Nonalcoholic fatty liver disease; HOMA: Homeostasis model assessment.

Table 3 Multiple linear regression, body mass index balanced, to non-alcoholic fatty liver disease disappearance - effects of changes

	All patients (n = 62)
	r	r2	F	Sig	β	P-value
	0.635	0.403	2.701	0.029
ADV36 seropositivity					0.408	0.013
Waist/hip ratio					0.018	0.907
ΔWeight, kg					0.413	0.057
ΔFM,%					0.433	0.012
ΔHOMA					0.189	0.284
ΔALT, U/L					0.279	0.095
ΔLongitudinal right liver (mm)					-0.154	0.386

Weighted least squares regression - weighted by BMI. Bold font indicates significant correlations. BMI: Body mass index; FM: Fat mass; ALT: Alanineaminotransferase; HOMA: Homeostasis model assessment.