Selection of appropriate endoscopic therapies for duodenal tumors: An open-label study, single-center experience

Table 1 Clinical characteristics of 15 endoscopic submucosal dissection and 31 endoscopic mucosal resection performed in 44 patients n (%)

	Total	ESD (n= 15)	EMR (n= 31)	Pvalue
Age, yr, mean ± SD (range)	65 ± 9 (35-79)	68 ± 5 (57-79)	64 ± 10 (35-77)	0.0775
Male/female	24/22	6/9	18/13	0.3480
Location in duodenum				0.0457
Bulb	15 (32.6)	8 (53.3)	7 (22.6)
Second portion	31 (67.4)	7 (46.7)	24 (77.4)
Size, mm, mean ± SD (range)	11.9 ± 9.7 (3-60)	12.9 ± 14.3 (3-60)	11.4 ± 6.7 (4-25)	0.6474
≥ 20 mm	8 (17.4)	2 (13.3)	6 (19.4)
< 20 mm	38 (82.6)	13 (86.7)	25 (80.6)
Macroscopic type				0.0009
Protruded	9 (19.6)	0	9 (29.0)
Elevated	21 (45.6)	4 (26.7)	17 (54.8)
Depressed	7 (15.2)	4 (26.7)	3 (9.7)
SMT	9 (19.6)	7 (46.6)	2 (6.5)
Histology				0.0044
Adenocarcinoma	6 (13.0)	2 (13.3)	4 (12.9)
Adenoma	31 (67.4)	6 (40.0)	25 (80.6)
NET	9 (19.6)	7 (46.7)	2 (6.5)

ESD: Endoscopic submucosal dissection; EMR: Endoscopic mucosal resection; SMT: Submucosal tumor; NET: Neuroendocrine tumor.

Table 2 Clinical outcomes of 15 endoscopic submucosal dissection and 31 endoscopic mucosal resection performed in 44 patients

	Total	ESD (n= 15)	EMR (n= 31)	Pvalue
En bloc resection rate	84.8%	86.7%	83.9%	> 0.9999
Complete resection rate	78.3%	86.7%	74.2%	0.4599
Procedure time, min, mean ± SD (range)	37.1 ± 51.4 (2-217)	86.5 ± 63.1 (15-217)	13.2 ± 17.0 (2-89)	< 0.0001
Complication	6 (13.0%)	5 (35.7%)	1 (3.4%)	0.0105
Perioperative perforation	3	3	0	0.0300
Perioperative bleeding	3	2	1	0.2444
Postoperative bleeding	1	1	0	0.3261
Emergency surgery	2	2	0	0.1014
Postoperative hospital stay, day, mean ± SD (range)	6.8 ± 2.5 (2-16)	8.2 ± 2.9 (5-16)	6.1 ± 2.0 (2-12)	0.0067