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May 28, 2014 (publication date) through Nov 6, 2025
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Publication Name
World Journal of Gastroenterology
ISSN
1007-9327
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study
Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. May 28, 2014; 20(20): 6314-6321
Published online May 28, 2014. doi: 10.3748/wjg.v20.i20.6314
Table 1 Demographic and clinical characteristics of patients with hepatocellular carcinoma for the study of tissue lncRNAs expression n (%)
ParametersDescriptionMinimumMaximum
Age (yr)56.59 ± 10.973073
Gender
Male26 (89.70)
Female3 (10.30)
Hepatitis virus infection
HBV22 (75.90)
HCV3 (10.30)
Negative4 (13.80)
Tumor size (cm)6.44 ± 3.65219
Tumor differentiation
Well6 (20.70)
Moderate16 (55.20)
Poor7 (24.10)
TNM stage
I10 (34.50)
II11 (37.90)
III7 (14.0)
IV1 (3.40)
BCLC stage
A21 (72.40)
B1 (3.40)
C7 (24.10)
AFP (ng/mL)
≤ 40017 (58.60)
> 40012 (41.40)
PVTT
Present23 (79.30)
Absent6 (20.70)
Tumor number
Single27 (93.10)
Multiple2 (6.90)
Capsule invasive
Present6 (20.70)
Absent23 (79.30)
ALP (U/L)42.90 ± 32.2411159
ALB (g/L)39.86 ± 3.722847
TBIL (μmol/L)15.36 ± 7.417.142.6
DBIL (μmol/L)6.10 ± 3.08316.5
Data are expressed as mean ± SD or n (%). TNM: Tumor-node-metastasis staging system; BCLC: The Barcelona Clinic Liver Cancer staging system; HBV: Hepatitis B virus; HCV: Hepatitis C virus; AFP: Alpha fetoprotein; PVTT: Portal vein tumor thrombus; ALP: Alkaline phosphatase; ALB: Albumin; TBIL: Total bilirubin; DBIL: Direct bilirubin.
Full Size Table
Table 2 The primer sequences used in this study
Target IDForward primerReverse primer
TCONS_00018278ATGAGGAACTGAGGTCTTTGGATTGAAGTTAGAGGGTCCAT
AK093543GCAGATTGATAAACCTACGGAACTTTCTCAGCAGTTTGTTATG
D16366TGACAATTCTGGGTGCGAAGAGAACCACAAGTACAGC
ENST00000501583TCACACTCTCACACTCGCATCGTCTGACTCTGGGTTC
NR_002819CAGCAGCAGACAGGATTCTTCCTTCACCAAATCGCAC
GAPDHTGTTGCCATCAATGACCCCTTCTCCACGACGTACTCAGCG
GAPDH: Glyceraldehyde-3-phosphate dehydrogenase.
Full Size Table
Table 3 The top twenty differentially expressed lncRNAs identified by the microarray in four hepatocellular carcinoma patients
lncRNAsFold change (Ca/Nt)Regulation direction
BC01539623.924885Up
NR_04633715.497891Up
ENST0000054249011.481871Up
Hs.56815210.981759Up
ENST0000054805710.762795Up
D1636610.744075Down
ENST0000054803610.218715Up
uc003bho.310.091635Up
TCONS_l2_000061159.758178Up
TCONS_l2_000061188.632748Up
AK0214437.991496Up
AY0277707.947163Up
TCONS_000075477.920387Up
Hs.1711927.900335Up
ENST000005689767.852221Up
TCONS_l2_000061137.546310Up
XR_1102257.462819Down
ENST000005001126.609479Up
ENST000005484756.573556Up
ENST000005272976.532015Up
Hepatocellular carcinoma samples (Ca) vs matched non-tumor (Nt).
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