Epithelial membrane protein 1 negatively regulates cell growth and metastasis in colorectal carcinoma

Table 1 Expression of epithelial membrane protein 1 in colorectal cancer tissue and normal colorectal tissue

Group	Case	Expression of epithelial membrane protein 1
		-	+	++	+++	χ2	P value
Normal tissue	31	3	6	11	12	25.239	0
Cancer tissue	63	38	10	8	7

Table 2 Relationship between epithelial membrane protein 1 expression and clinical characteristics of colorectal cancer

Variable	Case	Expression of epithelial membrane protein 1
		-	+-+++	χ2	P value
Sex
Male	37	21	16	0.199	0.656
Female	26	15	9
Age (yr)
≤ 60	46	27	19	0.187	0.665
> 60	17	11	6
Tumor location
Colon cancer	35	19	16	1.197	0.274
Rectal cancer	28	19	9
Tumor invasion
T1 + T2	27	11	16	7.566	0.006
T3 + T4	36	27	9
Lymph node metastasis
N0	28	11	17	9.314	0.002
N+	35	27	8
Clinical stage
I-II	25	9	16	10.240	0.001
III-IV	38	29	9
Histological grade
I	20	8	12	5.054	0.025
II-III	43	30	13