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©2014 Baishideng Publishing Group Co.
World J Gastroenterol. Apr 14, 2014; 20(14): 4001-4010
Published online Apr 14, 2014. doi: 10.3748/wjg.v20.i14.4001
Published online Apr 14, 2014. doi: 10.3748/wjg.v20.i14.4001
Table 1 Expression of epithelial membrane protein 1 in colorectal cancer tissue and normal colorectal tissue
| Group | Case | Expression of epithelial membrane protein 1 | |||||
| - | + | ++ | +++ | χ2 | P value | ||
| Normal tissue | 31 | 3 | 6 | 11 | 12 | 25.239 | 0 |
| Cancer tissue | 63 | 38 | 10 | 8 | 7 | ||
Table 2 Relationship between epithelial membrane protein 1 expression and clinical characteristics of colorectal cancer
| Variable | Case | Expression of epithelial membrane protein 1 | |||
| - | +-+++ | χ2 | P value | ||
| Sex | |||||
| Male | 37 | 21 | 16 | 0.199 | 0.656 |
| Female | 26 | 15 | 9 | ||
| Age (yr) | |||||
| ≤ 60 | 46 | 27 | 19 | 0.187 | 0.665 |
| > 60 | 17 | 11 | 6 | ||
| Tumor location | |||||
| Colon cancer | 35 | 19 | 16 | 1.197 | 0.274 |
| Rectal cancer | 28 | 19 | 9 | ||
| Tumor invasion | |||||
| T1 + T2 | 27 | 11 | 16 | 7.566 | 0.006 |
| T3 + T4 | 36 | 27 | 9 | ||
| Lymph node metastasis | |||||
| N0 | 28 | 11 | 17 | 9.314 | 0.002 |
| N+ | 35 | 27 | 8 | ||
| Clinical stage | |||||
| I-II | 25 | 9 | 16 | 10.240 | 0.001 |
| III-IV | 38 | 29 | 9 | ||
| Histological grade | |||||
| I | 20 | 8 | 12 | 5.054 | 0.025 |
| II-III | 43 | 30 | 13 | ||
- Citation: Sun GG, Wang YD, Cui DW, Cheng YJ, Hu WN. Epithelial membrane protein 1 negatively regulates cell growth and metastasis in colorectal carcinoma. World J Gastroenterol 2014; 20(14): 4001-4010
- URL: https://www.wjgnet.com/1007-9327/full/v20/i14/4001.htm
- DOI: https://dx.doi.org/10.3748/wjg.v20.i14.4001
