Prevention of liver metastasis by intraperitoneal 5-FU chemotherapy in nude mice inoculated with human colon cancer cells

Table 1 Metastatic nodules in the livers of experimental and control groups and controls ( x^-± s_x-, nodule)

Group	Liver metastatic nodules (n)					liver nodules (x-± s)
	0	1-20	21-40	41-60	61-80
5-FU 40 mga	4	2	1	1	2	24.80 ± 8.64
5-FU 20 mg	3	1	2	1	3	31.50 ± 8.68
Controls	0	2	1	3	4	50.50 ± 7.32

^aP < 0.05, vs controls

Table 2 Survival of mice in experimental and control groups

Group	Survival time (d)				Mean survival (d)
	21-30	31-40	41-50	51-60
5-FU 40 mg	3	1	0	6	45.50 ± 5.12a
5-FU 20 mg	3	1	2	4	43.90 ± 4.77a
Controls	6	2	2	0	30.70 ± 2.59

^aP < 0.05, vs controls