p53 gene mutations in primary gastric cancer

Table 1 p53 mutations in gastric cancer

Case	Stage1	Mutated exon
4	IIIa	5-6
6	II	7
7	Ib	5-6
8	II	7
10	Ib	8
13	0 (carcinoma in situ)	8
15	II	8
20	IIIa	8

¹According to the U.L.C.C. staging system.

Table 2 Histopathological parameters and p53 mutation in gastric cancer

Histopathological parameter	p53 mutation (%)
Macroscopic classification	1/3 (33.3)
Early gastric cancer
Advanced gastric cancer
Borrman I	0/1 (0)
Borrman II	2/3 (66.7)
Borrman III	4/11 (36.4)
Borrman IV	1/2 (50)
Degree of differentiation
Well	4/7 (57.1)
Poor	4/13 (30.8)
Depth of tumor invasion
Mucosa, submucosa layer	1/3 (33.3)
Muscular layer	6/13 (46.2)
Serous coat	1/4 (25)
Lymph node metastasis
Presence	4/13 (30.8)
Absence	4/7 (57.1)
Dna ploidy alteration
Diploid	2/11 (18.2)
Aneuploid	6/9 (66.7)