Comparison of different methods of intestinal obstruction in a rat model

Table 1 Criteria for scoring macromorphous intestinal damage

Feature	Description	Score
Adhesions	None	0
	Slight, ileum can be separated from other tissues with little effort	1
	Involved in a number of intestinal loops	2
Stenosis	None	0
	Slight	2
	Severe, proximal intestinal distention	3
Ulceration	None	0
	Damage extended to < 1 cm along the length at one site	1
	Damage extended to < 1 cm along the length at two sites	2
	Damage extended to > 1 cm along the length at one siteor multiple lesions	3
Bowel wall	< 1 mm	0
thickness	1-3 mm	1
	> 3 mm	2
Total score		10

Table 2 Criteria for scoring micromorphous intestinal damage

Feature	Description	Score
Ulceration	None	0
	Ulceration < 3 mm, no hyperemia or focal hyperemia, no ulceration	1
	Ulceration < 3 mm, with focal hyperemia or ulceration > 3 mm, without hyperemia	2
	Ulceration > 3 mm or hyperemia	3
Inflammation	None	0
	Slight	1
	Moderate	2
	Severe	3
Fibrogenesis	None	0
	Slight	1
	Severe	2
Extent of	None	0
involved	Submucosa	1
bowel wall	Muscular layer and even serosa	2
Total score		10

Table 3 Summary of daily general condition

General condition	Control				Braided silk				Half ligation				Wide pipe				Narrow pipe
	12 h	24 h	48 h	72 h	12 h	24 h	48 h	72 h	12 h	24 h	48 h	72 h	12 h	24 h	48 h	72 h	12 h	24 h	48 h	72 h
Body weight (E = 10)	-- → -				- → +				-				- → + +				--
Food intake (B = 5.0, E = 2.5)	±→ +				±→ --				+ →±				+ + →±				-
Feces
Dry weight (B = 1.0, E = 0.50)	- → + +				--				- → + +				- → --				- → +
Color	Yellow and black → Yellow				Yellow and black → Black				Yellow and black				Yellow and black				Yellow and black → Yellow
Pill (B =15, E =10)	±→ +				-- → -				±→ + +				- → --				- → +
Score (B = 20, E = 10)	- → +				-- → -				-- → + +				--				+ → + +
Death	+	±	±	±	+	±	++	+	++	±	±	+	+	±	±	+	±	±	++	++

B: Base value; E: Extent of increase and reduction; + +: Wider band increase (> E); +: Narrower band increase (< E); ±: No increase or reduction; -: Narrower band reduction (< E); --: Wider band reduction (> E). The values of the score are equal to pill multiplied by color. The color is defined by Yellow = 1, Yellow and black = 1.5, Black = 2.