Copyright
©2013 Baishideng Publishing Group Co.
World J Gastroenterol. Aug 28, 2013; 19(32): 5227-5237
Published online Aug 28, 2013. doi: 10.3748/wjg.v19.i32.5227
Published online Aug 28, 2013. doi: 10.3748/wjg.v19.i32.5227
Ref. | No. of patients | Neoadjuvant therapy regimen | Time interval1 (wk) | No. of patients with ypT0/T1 | ||
Radiotherapy (Gy) | Chemotherapy | ypN+/ypT0-1 | ypN+/ypT2-4 | |||
Zmora et al[42] | 109 | 45-50.4 | 5-Fu | 6 | 4/33 (12.1) | 30/61 (49.2) |
Read et al[43] | 644 | 20-45 | 5-Fu | NS | 3/87 (3.4) | 217/557 (39.0) |
Bujko et al[44] | 147 | 5 × 5 | 1 | 0/4 (0.0) | 69/138 (50.0) | |
Bujko et al[44] | 138 | 50.4 | 5-Fu | 4-6 | 2/33 (6.1) | 41/101 (40.6) |
Pucciarelli et al[45] | 235 | 45-50.4 | 5-Fu | 6-8 | 3/69 (4.3) | 45/166 (27.1) |
Tulchinsky et al[46] | 101 | 45 | 5-Fu | 5-7 | 1/22 (4.5) | 29/75 (38.7) |
Habr-Gama et al[47] | 401 | 50.4 | 5-Fu | 8 | 3/25 (10.7) | 75/224 (33.5) |
Stipa et al[48] | 187 | 50.4 | 5-Fu | NS | 3/44 (6.8) | 48/143 (33.6) |
Kundel et al[49] | 320 | 45 | 5-Fu | 4-8 | 3/69 (4.3) | 49/222 (22.1) |
Gavioli et al[31] | 139 | 50 | 5-Fu | 4 | 2/34 (5.9) | 38/105 (36.2) |
Kim et al[50] | 282 | 45 | 5-Fu | 4-8 | 2/58 (3.4) | 85/224 (37.9) |
Lindebjerg et al[51] | 135 | 60 | 5-Fu | 8 | 8/47 (17.0) | 32/88 (36.4) |
Coco et al[52] | 271 | NS | NS | NS | 3/71 (4.2) | 70/200 (35.0) |
Total | 3109 | 37/596 (6.2) | 828/2304 (35.9) |
Ref. | No. of patients | Neoadjuvant therapy regimen | No. of LR | ||
Radiotherapy (Gy) | Chemotherapy | pCR LR/total | Non-pCR LR/total | ||
Gavioli et al[31] | 139 | 50 | 5-Fu | 0/25 (0.0) | 8/114 (7.0) |
Stipa et al[57] | 200 | 50 | 5-Fu | 0/60 (0.0) | 6/140 (4.3) |
Hughes et al[71] | 130 | 45 | 5-Fu | 0/23 (0.0) | 23/107 (17.7) |
Kim et al[82] | 114 | 50.4 | 5-Fu | 0/10 (0.0) | 17/104 (16.3) |
Kuo et al[83] | 248 | 50 | 5-Fu | 2/36 (5.6) | 66/212 (31.1) |
Chan et al[84] | 128 | 50 | 5-Fu | 0/32 (0.0) | 24/96 (18.4) |
García-Aguilar et al[86] | 168 | 40-65 | 5-Fu | 0/21 (0.0) | 7/147 (5) |
Wheeler et al[87] | 63 | 45-50 | 5-Fu | 1/29 (3.4) | 8/34 (23.5) |
Theodoropoulos et al[88] | 88 | 45 | 5-Fu | 0/16 (0.0) | 3/72 (4.2) |
Total | 1278 | 3/252 (1.2) | 162/1026 (15.8) |
- Citation: Peng JY, Li ZN, Wang Y. Risk factors for local recurrence following neoadjuvant chemoradiotherapy for rectal cancers. World J Gastroenterol 2013; 19(32): 5227-5237
- URL: https://www.wjgnet.com/1007-9327/full/v19/i32/5227.htm
- DOI: https://dx.doi.org/10.3748/wjg.v19.i32.5227