Protective effects of two Lactobacillus plantarum strains in hyperlipidemic mice

Table 1 Effects on body weight, diet intake, liver index, and serum lipid levels

Group	NM	NM/CAI6	NM/SC4	HM	HM/CAI6	HM/SC4
Body weight, food intake, and liver index of normal model and hyperlipidemic model mice after treatment for 30 d
IBW (g)	26.53 ± 2.96	25.47 ± 2.71	27.03 ± 2.09	33.17 ± 1.44b	31.32 ± 1.06b	30.78 ± 1.66b
FBW (g)	33.43 ± 4.78d	28.50 ± 3.56d	32.30 ± 2.73d	39.05 ± 2.50b	36.68 ± 2.22	38.08 ± 1.87a
TFI (g)	44.76 ± 6.94	47.07 ± 4.04	47.05 ± 2.51	52.29 ± 11.97	51.09 ± 6.34	53.32 ± 13.14
1LI (%)	4.11 ± 0.30	4.08 ± 0.15	4.10 ± 0.49	4.65 ± 0.50	4.41 ± 0.58	4.54 ± 0.64
Serum lipid levels in the different groups of mice
TC (mmol/L)	2.89 ± 0.36d	2.60 ± 0.24c	2.85 ± 0.28a	3.50 ± 0.43b	3.16 ± 0.35	3.27 ± 0.36
TG (mmol/L)	1.10 ± 0.16d	1.06 ± 0.15d	1.08 ± 0.13d	1.76 ± 0.07b	1.43 ± 0.27d	1.54 ± 0.10a
HDL-C (mmol/L)	1.62 ± 0.52	1.76 ± 0.48a	1.67 ± 0.14	1.20 ± 0.42	1.36 ± 0.55	1.31 ± 0.55
LDL-C (mmol/L)	0.82 ± 0.10d	0.75 ± 0.07	0.81 ± 0.09	1.72 ± 0.20b	1.42 ± 0.07d	1.47 ± 0.12d
2AI	0.93 ± 0.55a	0.57 ± 0.41d	0.71 ± 0.09d	2.34 ± 1.60a	1.65 ± 0.99	1.94 ± 1.47
LDL-C/HDL-C	0.51 ± 0.16a	0.43 ± 0.19d	0.49 ± 0.04d	1.43 ± 0.12a	1.04 ± 0.16	1.12 ± 0.14

Data represent mean ± SD (n = 6 for each group).

¹LI: Weight of liver (mg)/body weight (g),

²AI = (TC-HDL-C)/HDL-C,

^aP < 0.05 vs NM group,

^bP < 0.01 vs NM group,

^dP < 0.01 vs HM group. IBW: Initial body weight; FBW: Final body weight; TFI: Total feed intake; LI: Liver index; TC: Total cholesterol; TG: Triglyceride; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol; AI: Atherogenic index; NM: Normal diet group; HM: High-cholesterol diet group; NM/CAI6: Normal diet with Lactobacillus plantarum (L. plantarum) CAI6 group; NM/SC4: Normal diet with L. plantarum SC4 group; HM/CAI6: High-cholesterol diet with L. plantarum CAI6 group; HM/SC4: High-cholesterol diet with L. plantarum SC4 group.