Effect of Danzhijiangtang capsule on monocyte chemoattractant protein-1 mRNA expression in newly diagnosed diabetes subclinical vascular lesions

Table 1 Comparison of fasting plasma glucose, 2-h plasma glucose, haemoglobin A1c, fasting insulin, insulin resistance index, total cholesterol, triglycerides, low density lipoprotein, high density lipoprotein, haemorheology indices, thrombomodulin, von Willebrand factor, P-selectin levels and monocyte chemoattractant protein-1 mRNA levels

Index	Control group		Treatment group
	Before treatment (n = 31)	After treatment (n = 29)	Before treatment (n = 31)	After treatment (n = 30)
FPG (mmol/L)	8.74 ± 1.42	8.01 ± 1.09b	9.02 ± 1.14	7.94 ± 0.91b
2hPG (mmol/L)	12.42 ± 1.76	10.03 ± 1.39b	11.96 ± 1.53	9.81 ± 1.34b
HbA1c (%)	7.98 ± 0.71	7.11 ± 0.69b	8.03 ± 0.68	6.98 ± 0.65b
FINS (uIU mL-1)	12.05 ± 2.93	8.68 ± 1.83b	11.93 ± 2.45	7.58 ± 1.82bc
IRI	1.81 ± 0.24	1.60 ± 0.19b	1.79 ± 0.23	1.48 ± 0.19bc
TC (mmol/L)	5.36 ± 0.76	4.55 ± 0.59b	5.27 ± 0.69	4.32 ± 0.49b
TG (mmol/L)	2.01 ± 0.38	1.78 ± 0.36a	1.99 ± 0.42	1.76 ± 0.31a
LDL (mmol/L)	3.15 ± 0.31	3.06 ± 0.29a	3.24 ± 0.28	3.07 ± 0.28a
HDL (mmol/L)	1.41 ± 0.19	1.66 ± 0.17b	1.37 ± 0.21	1.77 ± 0.15bc
High shear specific viscosity (mPa.s)	5.37 ± 0.78	5.10 ± 0.71	5.43 ± 0.65	4.73 ± 0.54bc
Low shear specific viscosity (mPa.s)	12.65 ± 0.89	11.91 ± 1.02	12.51 ± 0.92	11.84 ± 0.94b
Hematocrit (%)	42.95 ± 3.69	42.89 ± 3.51	43.15 ± 4.31	41.98 ± 3.01
Plasma specific viscosity (mPa.s)	1.93 ± 0.35	1.72 ± 0.37	2.01 ± 0.31	1.54 ± 0.24bc
Fibrinogen (mg/L)	4.52 ± 0.48	4.36 ± 0.37	4.61 ± 0.38	4.39 ± 0.35
TM (μg/L)	25.68 ± 6.54	23.27 ± 4.06	25.41 ± 6.28	19.32 ± 4.29ac
vWF (U/L)	1540.17 ± 74.70	1480.66 ± 72.32	1551.92 ± 82.23	1146.70 ± 94.45b,d
P-selectin (ng/mL)	25.03 ± 6.06	22.57 ± 5.56	25.39 ± 6.81	17.08 ± 5.82ac
MCP-1 mRNA (%)	0. 537 ± 0. 136	0.473 ± 0.134a	0. 541 ± 0. 148	0.421 ± 0.132bc

^aP < 0.05,

^bP < 0.01 vs before treatment;

^cP < 0.05 vs control group. FPG: Fasting plasma glucose; 2hPG: 2-h plasma glucose; HbA1c: Haemoglobin A1c; FINS: Fasting insulin; IRI: Insulin resistance index; TC: Total cholesterol; TG: Triglycerides; LDL: Low density lipoprotein; HDL: High density lipoprotein; TM: Thrombomodulin; vWF: von Willebrand factor; MCP-1: Monocyte chemoattractant protein-1.