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©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Jan 28, 2012; 18(4): 388-392
Published online Jan 28, 2012. doi: 10.3748/wjg.v18.i4.388
Published online Jan 28, 2012. doi: 10.3748/wjg.v18.i4.388
IRF3 | Chronic HBV infection | Acute HBV infection | P value | OR (95% CI) |
rs10415576 | n = 985 | n = 294 | ||
AA | 347 (35.23) | 119 (40.48) | 1.0 | |
GG | 135 (13.71) | 33 (11.22) | 0.125 | 1.4029 (0.9091-2.1650) |
AG | 503 (51.07) | 142 (48.30) | 0.172 | 1.2148 (0.9187-1.6063) |
A | 1197 (60.76) | 380 (64.63) | 0.091 | 1.1798 (0.9740-1.4291) |
G | 773 (39.24) | 208 (35.37) | ||
rs2304204 | n = 985 | n = 294 | ||
AA | 542 (55.03) | 166 (56.46) | ||
GG | 54 (5.48) | 14 (4.76) | 0.594 | 1.1813 (0.6400-2.1807) |
AG | 389 (39.49) | 114 (38.78) | 0.75 | 1.0451 (0.7965-1.3713) |
A | 1473 (74.77) | 446 (75.85) | 0.596 | 1.0579 (0.8552-1.3133) |
G | 497 (25.23) | 142 (24.15) | ||
rs2304206 | n = 985 | n = 294 | ||
CC | 639 (64.87) | 191 (64.97) | 1.0 | |
TT | 30 (3.05) | 7 (2.38) | 0.562 | 1.2810 (0.5539-2.9627) |
CT | 316 (32.08) | 96 (32.65) | 0.909 | 0.9839 (0.7437-1.3016) |
C | 1594 (80.91) | 478 (81.29) | 0.837 | 1.0250 (0.8097-1.2976) |
T | 376 (19.09) | 110 (18.71) |
Haplotypes | Frequency(cases) | Frequency(controls) | χ2 | P value | OR (95% CI) |
AAC | 0.6066 | 0.6446 | 2.8246 | 0.0929 | 1.1787 (0.9729-1.4279) |
GAC | 0.1411 | 0.1139 | 2.8473 | 0.0916 | 0.7833 (0.5895-1.0408) |
GGC | 0.0609 | 0.0527 | 0.5420 | 0.4616 | 0.8586 (0.5721-1.2888) |
GGT | 0.1904 | 0.1871 | 0.0293 | 0.8642 | 0.9796 (0.7738-1.2402) |
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Citation: Yan F, Gao YF, Lv F, Zhang TC, Li X, Yin HF. No association between
IRF3 polymorphism and susceptibility to hepatitis B virus infection in Chinese patients. World J Gastroenterol 2012; 18(4): 388-392 - URL: https://www.wjgnet.com/1007-9327/full/v18/i4/388.htm
- DOI: https://dx.doi.org/10.3748/wjg.v18.i4.388