Temporal trends in the relative prevalence of dysphagia etiologies from 1999-2009

Table 1 Baseline demographic data and relative prevalence of dysphagia etiologies from 1999-2009 n (%)

	1999	2004	2009	P value
Total EGDs performed	2456	5944	9071	--
Total included EGDs for dysphagia	191	504	675	--
Excluded EGDs for dysphagia	46 (19.4)	9 (1.8)	53 (7.3)	< 0.001
Age (yr), mean (SD)	55.5 (16.1)	54.0 (15.7)	52.3 (16.8)	NS
Male sex (%)	57.5	40.8	40.7	0.005
EGD with biopsy performed	70 (36.7)	189 (37.5)	464 (68.7)	< 0.001
Diagnosis
Non-obstructive GERD	75 (39.3)	140 (27.7)	163 (24.1)	< 0.001
Eosinophilic esophagitis	3 (1.6)	27 (5.4)	76 (11.2)	< 0.001
Achalasia	9 (4.7)	26 (5.1)	27 (4.0)	NS
Other motility disorder	4 (2.1)	30 (5.8)	30 (4.4)	NS
Peptic stricture	2 (1.0)	11 (2.1)	18 (2.6)	NS
Schatzki's ring	10 (5.2)	19 (3.7)	25 (3.7)	NS
Esophageal cancer	8 (4.2)	19 (3.7)	15 (2.2)	NS
Post-operative	6 (3.1)	31 (6.1)	25 (3.7)	NS
Oropharyngeal dysphagia	3 (1.6)	11 (2.1)	32 (4.7)	0.02
Radiation esophagitis	6 (3.1)	17 (3.4)	15 (2.2)	NS
Infectious esophagitis	5 (2.6)	13 (2.5)	19 (2.8)	NS
Unspecified	47 (24.6)	103 (20.4)	138 (20.4)	NS
Other1	13 (6.8)	54 (10.7)	88 (13.0)	NS

¹Including: Cricopharyngeal bar, globus, functional dysphagia, diverticulum, scleroderma and epidermolysis bullosa with proximal stricture. Statistical analysis performed using one-way analysis of variance. GERD: Gastroesophageal reflux disease; EGDs: Upper endoscopies; NS: Non-significant.