Anticoagulation therapy prevents portal-splenic vein thrombosis after splenectomy with gastroesophageal devascularization

Table 1 Comparison of preoperative data between two groups

	Irregular anticoagulation (group A)	Regular anticoagulation (group B)	P value
Sex (M/F)	103/50	99/49	0.937
Age (yr), mean ± SD	46.14 ± 10.39	46.47 ± 9.58	0.814
Type of disease
Hepatitis B viral cirrhosis	128	126	0.816
Hepatitis C viral cirrhosis	11	8
Alcoholic cirrhosis	11	11
Idiopathic portal hypertension	1	2
Biliary cirrhosis	2	1
Child-Pugh classification (grade A/grade B)	121/32	125/23	0.228
MELD index: mean ± SD, median	7.68 ± 3.24, 7.70	6.62 ± 2.76, 6.51	0.055
History of upper GI bleeding	125 (81.69%)	111 (75%)	0.158
History of GI ulcer	18 (11.76%)	23 (15.54%)	0.340
Preoperative portal vein diameter (mm): mean ± SD, median	12.38 ± 1.17, 13	12.90 ± 1.20, 12	0.083
Preoperative splenic vein diameter (mm): mean ± SD, median	9.85 ± 1.69, 10	10.10 ± 1.41, 10	0.551

MELD: Model for end-stage disease; GI: Gastrointestinal.

Table 2 Distribution of thrombi in two groups, n (%)

Location	Irregular anticoagulation (group A)	Regular anticoagulation (group B)
Simple PV main trunk mural thrombosis	31 (20.26)	18 (12.16)
Simple splenic vein mural thrombosis	12 (7.84)	4 (2.70)
Complicated portal and splenic vein thrombosis	19 (12.41)	7 (4.72)
Simple SMV thrombosis	1 (0.65)	0
Complicated portal PV and SMV thrombosis	0	2 (1.35)
Total	63	31
Incidence of thrombosis	(41.17)	(20.94)

χ² = 15.009, P = 0.002. PV: Portal vein; SMV: Superior mesenteric vein.