Evaluation of non-ampullary duodenal polyps: Comparison of non-neoplastic and neoplastic lesions

Table 1 Lesions in the ampulla of vater and submucosal lesions of the duodenum

Histologic diagnosis	No. (n = 44)
Lesions in the ampulla of vater
Adenoma	12
Focal carcinomatous change	1
Inflammatory myofibroblastic tumor	1
Carcinoid	1
Submucosal lesions
Lipoma	14
Cyst	9
Lymphangioma	3
Gastrointestinal stromal tumor	2

Table 2 Non-neoplastic lesions and neoplastic lesions

Non-neoplastic lesions	No. (n = 196)	Neoplastic lesions	No. (n = 25)
Brunner’s gland hyperplasia	17	Adenoma	14
Brunner’s gland hamartoma	4	Serrated adenoma	1
		Focal cancer change in adenoma	1
	Ectopic gastric mucosa	12	Originated in Brunner’s gland	1
Ectopic pancreas	1	In familial adenomatosis polyposis	1
Hyperplastic polyp	29	Carcinoid tumor	6
Inflammatory polyp	33
Normal pathology	100	Metastatic cancer	1

Table 3 Characteristics of non-neoplastic and neoplastic lesions

	Non-neoplastic(n = 196)	Neoplastic lesions (n = 25)	P value
Sex			0.661
Male	122	17
Female	74	8
Age (yr)	56.17 ± 12.70	60.04 ± 11.24	0.142
Shape			< 0.011
Sessile	170	16
Pedunculated	26	9
Location			< 0.011
Bulb	156	13
2nd portion	40	12
Size (cm)	0.65 ± 0.42	1.46 ± 0.76	< 0.012
Multiplicity	26	2	0.713

¹Calculated by Pearson χ² test;

²Calculated by Mann-Whitney U-test;

³Calculated by Fisher exact test.

Table 4 Independent risk factors identified on multivariate analysis

Total	Odds ratio	95% CI	P value
Type	1.56	0.54-4.46	0.41
Sessile
peduncle
Location	3.55	1.32-9.54	0.01
Bulb
2nd portion
Size (cm)	14.12	4.99-39.99	< 0.01
< 1.0
≥ 1.0

Table 5 Frequencies of gastroduodenal lesions associated with duodenal hyperplastic polyps

	n (%)
Peptic ulcer	24.1 (7)
Gastric cancer	3.4 (1)
Chronic atrophic gastritis	58.6 (17)
Gastroesophageal reflux disease	10.3 (3)
Gastric hyperplastic polyp	6.8 (2)
Miscellaneous1	6.8 (2)

¹Gastric varix, gastric submucosal tumor.