Evaluation of non-ampullary duodenal polyps: Comparison of non-neoplastic and neoplastic lesions

doi:10.3748/wjg.v16.i43.5474

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Nov 21, 2010 (publication date) through Nov 20, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 21, 2010; 16(43): 5474-5480
Published online Nov 21, 2010. doi: 10.3748/wjg.v16.i43.5474

Evaluation of non-ampullary duodenal polyps: Comparison of non-neoplastic and neoplastic lesions

Sung Hoon Jung, Woo Chul Chung, Eun Jung Kim, Seol Hye Kim, Chang Nyol Paik, Bo In Lee, Young Seok Cho, Kang-Moon Lee

Sung Hoon Jung, Woo Chul Chung, Eun Jung Kim, Seol Hye Kim, Chang Nyol Paik, Bo In Lee, Young Seok Cho, Kang-Moon Lee, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 137-701, South Korea

Author contributions: Jung SH and Chung WC collected the data and designed the research; Kim EJ, Kim SH, Paik CN, Lee BI, Cho YS and Lee KM contributed to the paper’s conception and carried out the literature research; Jung SH and Chung WC analyzed the data and wrote the paper.

Correspondence to: Woo Chul Chung, MD, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, St. Vincent’s Hospital Ji-dong, Paldal-gu, Suwon Si, Gyeonggi-Do 442-723, South Korea. jwchulkr@yahoo.co.kr

Telephone: +82-31-2497138 Fax: +82-31-2538898

Received: February 16, 2010
Revised: April 19, 2010
Accepted: April 26, 2010
Published online: November 21, 2010

Abstract

AIM: To evaluate duodenal polyps, divided into non-neoplastic and neoplastic lesions. In addition, the clinical characteristics of duodenal hyperplastic polyps are determined.

METHODS: We analyzed medical records of 50 114 consecutive patients submitted to for first diagnostic esophago-gastroduodenoscopy between January 2004 and December 2009. We excluded lesions on the ampulla of Vater and submucosal tumors. We studied 510 cases that were diagnosed endoscopically with duodenal polyps and enrolled a total of 221 cases that had undergone tissue biopsy. We analyzed the differences between non-neoplastic and neoplastic lesions, and determined the clinical features of duodenal hyperplastic polyps.

RESULTS: Non-neoplastic lesions were found in 196 patients and neoplastic lesions in 25 patients. On univariate analysis, there were significant differences in shape, location, and size. Polyps more than 10 mm in diameter or polyps in the second portion had independent risk factors for being neoplastic lesions, as identified by multivariate analysis. In 23 cases of hyperplastic polyps (79.3%), they were accompanied by gastro-duodenal pathology, which was possibly associated with Helicobacter pylori.

CONCLUSION: Polyps of more than 10 mm or polyps in the second portion of the duodenum should be evaluated by histological examination.

Keywords: Duodenum; Polyp; Helicobacter pylori