Limited endoscopic sphincterotomy plus large balloon dilation for choledocholithiasis with periampullary diverticula

Table 1 Baseline characteristics of patients with common bile duct stones who also had periampullary diverticula (periampullary diverticula group) or did not have periampullary diverticula (control group), median (range)

Characteristics	PAD group	PAD subtypes			Control group	P2value
		Type A	Type B	P1 value
No. of patients	73	35 (47.9)	38 (52.1)		66
M:F	36:37	19:16	17:21	NS	39:27	NS
Age (yr)	70 (40-89)	74 (54-88)	66.5 (40-89)	NS	64 (23-89)	< 0.001
CBD diameter (mm)	15 (10-30)	16 (10-26)	15 (10-30)	NS	15 (11-38)	NS
Size of stones (mm)	14 (10-33)	14 (10-30)	14 (10-33)	NS	12 (10-35)	NS
No. of stones	2 (1-20)	2 (1-9)	2 (1-20)	NS	2 (1-7)	NS
Distal CBD stricture	4	3	1	NS	1	NS
Needle-knife fistulotomy	7	3	4	NS	11	NS

¹Comparing between subgroups of periampullary diverticula (PAD); ²Comparing PAD group with control group. CBD: Common bile duct; NS: Not significant.

Table 2 Outcome of limited endoscopic sphincterotomy plus large balloon dilation in patients with common bile duct stones who also had periampullary diverticula (periampullary diverticula group) or did not have periampullary diverticula (control group)

Characteristics	PAD group	Control group	P2value
Overall stone removal, n (%)	69/73 (94.5)	62/66 (93.9)	NS
Type A	33/35 (94.3)		NS
Type B	36/38 (94.7)		NS
P1 value	NS
Stone removal in first session, n (%)	51/73 (69.9)	54/66 (81.8)	NS
Type A	28/35 (80)		NS
Type B	23/38 (60.5)		0.021
P1 value	NS
No. of sessions, median (range)	1 (1-3)	1 (1-2)	NS
Type A	1 (1-3)		NS
Type B	1 (1-3)		0.037
P1 value	NS
Diameter of balloon dilation (mm), median (range)	13.5 (10-20)	12.5 (10-20)	NS
Type A	13.5 (10-20)		NS
Type B	13.8 (10-20)		NS
P1 value	NS
Mechanical lithotripsy required, n (%)	9/73 (12.3)	9/66 (13.6)	NS
Type A	5/35 (14.3)		NS
Type B	4/38 (10.5)		NS
P1 value	NS

¹Comparing between subgroups of periampullary diverticula (PAD); ²Comparing PAD group with control group. NS: Not significant.

Table 3 Complications of limited endoscopic sphincterotomy plus large balloon dilation in patients with common bile duct stones who also had periampullary diverticula (periampullary diverticula group) or did not have periampullary diverticula (control group) n (%)

Complications	PAD group	Control group	P2value
Pancreatitis	7/73 (9.6)	2/66 (3.0)	NS
Type A	5/35 (14.3)		0.047
Type B	2/38 (5.3)		NS
P1 value	NS
Hemorrhage	0/73 (0)	1/66 (1.5)	NS
All complications	7/73 (9.6)	3/66 (4.5)	NS
Type A	5/35 (14.3)		NS
Type B	2/38 (5.3)		NS
P1 value	NS

¹Comparing between subgroups of periampullary diverticula (PAD); ²Comparing PAD group with control group. NS: Not significant.