α,β-amyrin, a natural triterpenoid ameliorates L-arginine-induced acute pancreatitis in rats

Table 1 Effects of α,β-amyrin treatment on morphological signs of pancreatic damage

Group	Edema (0-3)	Inflammatory infiltration (0-3)	Acinar vacuolization (0-3)	Hemorrhage (0-3)	Necrosis (0-3)
Saline control	0 (0-0)	0 (0-0)	0 (0-0)	0 (0-0)	0 (0-0)
Vehicle + L-arginine	3 (2-3)a	2 (2-3)a	3 (3-3)a	2 (2-3)a	3 (3-3)a
α,β-amyrin (100 mg/kg) + L-arginine	0 (0-0)c	0 (0-0)c	0 (0-1)c	0 (0-0)c	0 (0-0)c
Pred + L-arginine	0 (0-1)c	0 (0-0)c	1 (0-1)c	0 (0-1)c	0 (0-0)c

Median scores with ranges (min-max) of the results in six animals in each group are shown.

^aP < 0.05 vs saline control group;

^cP < 0.05 vs vehicle + L-arginine group. Pred: Methylprednisolone.