Pedunculated hepatocellular carcinoma and splenic metastasis

Table 1 Previous cases reported in literature with HCC and splenic metastasis

Authors	Age (yr)/sex	Metastasis type	Clinical manifestations	Intrahepatic metastasis at time of splenic metastasis	Metastasis to other organs
Filik et al[6]	62/W	H	Severe ascites and abdominal pain	Multiple HCC	None
	47/M	H	Right flank of pain	HCC	None
Hanada et al[7]	59/M	H	Asymptomatic	Multiple HCC	Adrenal gland
	69/W	H	Not described	None	None
	67/M	H	Not described	None	Lung
Yamamoto et al[11]	68/W	H	Abdominal fullness	Single HCC	None
	61/M	H	Swelling cervical lymph nodes	HCC	Cervical lymph nodes
Fujimoto et al[12,13]	62/M	H	LUQ mass	None	None
	62/M	H	Spontaneous rupture of spleen	HCC	None
Horie et al[14]	62/W	H	Spontaneous rupture of spleen	HCC	None
Katoh et al[17]	55/M	H	Not described	HCC	None
Iwaki et al[8]	60/M	H	Asymptomatic	Multiple HCC	Lung and jejunal
Sumiya et al[16]	78/M	H	Spontaneous rupture of spleen	None	Lung
Hayashi et al[15]	76/M	H	Asymptomatic	None	None
Hama et al[9]	61/M	H	Asymptomatic	Multiple HCC	Lung
Nakamura et al[10]	54/M	H	Asymptomatic	Multiple HCC	Lung

HCC: Hepatocellular carcinoma; H: Hematogenous metastasis; LUQ: Left upper quadrant.