Milk protein IgG and IgA: The association with milk-induced gastrointestinal symptoms in adults

Table 1 Data of the study group, the experienced symptoms and correlation of milk protein IgG and IgA levels with different parameters

Subjects	N (% of the study group)	Mean IgG% (arbitrary units) 95% CI (lower-upper)	P	Mean IgA% ( arbitrary units)95% CI (lower-upper)	P
Study group (yr)	388	13.5 (11.5-15.5)		7.3 (55-9.2)
18-34	139 (35)	16.6 (13.1-20.2)	< 0.0041	9.4 (5.5-13.2)	0.16
35-49	123 (32)	14.7 (10.7-10.8)		7.4 (4.1-10.6)
50-64	126 (33)	8.8 (6.5-11.1)		5.1 (3.1-6.9)
Male	195 (50)	14.0 (11.2-16.7)	0.5	7.7 (5.1-10.3)	0.042
Female	193 (50)	13.0 (10.2-15.9)		7.0 (4.4-9.6)
Drinking milk daily	265 (68)	15.4 (12.8.-18.0)	< 0.0013	7.8 (5.6-10.0)
Not drinking milk	123 (32)	9.3 (6.5-12.1)		6.4 (3.2.-9.7)
Subjective symptoms from milk	119 (31)	10.5 (7.6-13.5)	0.024	6.4 (2.5-10.3)	0.5
No subjective symptoms from milk	198 (51)	16.0 (12.8-19.1)		8.0 (5.7-10.4)
Constipation	47 (12)	19.2 (11.7-26.8)	0.05	11.3 (3.7-18.8)	0.06
No constipation	282 (73)	13.3 (11.0-15.6)		7.5 (5.4-9.7)
Diarrhea	133 (34)	14.4 (11.0-17.8)		8.0 (4.4.-11.6)	0.7
No diarrhea	196 (51)	14.0 (11.0-17.0)		8.1 (5.5.-10.8)
Dyspepsia	127 (33)	11.9 (8.5.-15.3)	< 0.055	4.8 (300-668)	0.1
No dyspepsia	202 (52)	15.6 (12.6-18.5)		10.1 (6.8-13.3)

¹The level of IgG decreased according to the age statistically significantly.

²The IgA level was statistically significantly higher in men than in women.

³The milk drinking was associated with IgG level statistically significantly.

⁴The IgG level was statistically significantly higher in subjects with symptoms from milk.

⁵The level of IgG was statistically significantly lower in subjects with dyspepsia.