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©2008 The WJG Press and Baishideng.
World J Gastroenterol. Dec 7, 2008; 14(45): 6999-7004
Published online Dec 7, 2008. doi: 10.3748/wjg.14.6999
Published online Dec 7, 2008. doi: 10.3748/wjg.14.6999
Table 1 Hydroxycut ingredients supplement facts (serving size 2 caplets)
| Amount per serving | % daily value |
| Calcium (as hydroxycitrate) 156 mg | 161 |
| Chromium (as polynicotinate) 133 mg | 1111 |
| Potassium (as hydroxycitrate) 218 mg | 61 |
| Garcinia Cambogia (66% hydroxycitric acid) | 2 |
| Gymnema Sylvestre (25% gymnemic acid) | 2 |
| Soy Phospholipids | 2 |
| Rhodiola rosea extract (5% rosavins) | 2 |
| Green Tea as Camelia Sinensis (91 mg of EGCG) | 2 |
| White Tea as Camelia Sinensis ( 15% EGCG) | 2 |
| Oolong Tea as Camelia Sinensis (15% EGCG) | 2 |
| Caffeine anhydrous | 2 |
Table 2 Components of popular weight loss supplements
| Brand name | Potentially hepatotoxic components |
| Hydroxycut | Garcinia Cambogia, Chromium, Camelia Sinensis |
| Ephedrasile Hardcore | C. Sinensis, Valerian, St John’s wort |
| Zalestrim | C. Sinensis. Black Cohosh, Dong Quai |
| Slim-Citi | Hoodia |
| Ephedra | Mau Hang |
| Leptoril | C. Sinenis, Aspirin |
| Adipokinetix | C. Sinensis |
| Xenadrine | C. Sinensis, Ma Huang |
| Lipovox | C. Sinensis |
| Lean fire | C. Sinensis |
| Miracle Burn | Hoodia |
| 7 DFB | Noni extract |
| Curvatrim | C. Sinensis, Dong Quai |
| Ambi-Slim | C. Sinensis, Garcinia Cambogia, Chromium, Valerian |
| TrimSpaX32 | C. Sinensis, Hoodia Gordoni |
| Eroved | Hoodia, Garcinia Cambogia, Chromium |
| Zylorin | Hoodia, C. Sinensis, Chromium |
| Jet Fuel | C. Sinensis, Hoodia, |
| VPX redline | C. Sinensis |
| Metabolene | C. Sinensis, Chromium, Hoodia |
Table 3 Patterns of injury in herbal hepatotoxicity
| Cholestatic | Hepatocellular | Autoimmune | Fulminant failure | |
| Atractylis Gummifera[50] | X | |||
| Black Cohosh [51,52] | X | X | ||
| Callilepsis Laureola[53] | X | |||
| Camelia Sinensis[24-28] | X | X | ||
| Chapparral[54] | X | X | ||
| Chromium picolinate[18,19] | X | |||
| Cascara Sagrada[55] | X | |||
| Dai-Saiko-To[5] | X | |||
| Garcinia Cambogia[7] | X | X | ||
| Germander[56,57] | X | X | ||
| Greater Celadine[58,59] | X | X | ||
| Jin Bu Huan[60] | X | |||
| Kava[61-63] | X | |||
| Noni[64] | X | |||
| Paeonia[65] | X | |||
| Paulina Cupana | X | |||
| Penny Royal[66,67] | X | |||
| Senna[68] | X | |||
| Shou wu pian[5] | X | |||
| Syo-Saiko-To[69] | X | X | ||
| Teucrium Polium[5] | X | |||
| Usnic Acid[70,71] | X | X | ||
| Valerian[72] | X |
- Citation: Dara L, Hewett J, Lim JK. Hydroxycut hepatotoxicity: A case series and review of liver toxicity from herbal weight loss supplements. World J Gastroenterol 2008; 14(45): 6999-7004
- URL: https://www.wjgnet.com/1007-9327/full/v14/i45/6999.htm
- DOI: https://dx.doi.org/10.3748/wjg.14.6999