Cytoreduction and hyperthermic intraperitoneal chemotherapy in the treatment of peritoneal carcinomatosis from pseudomyxoma peritonei

Table 1 Extent of CCR and HIPEC in 53 patients affected by PMP

Procedures	No.
Greater omentectomy	48
Left colectomy	30
Right colectomy	34
Total abdominal hysterectomy	16
Bilateral salpingo-oophorectomy	20
Splenectomy	40
Cholecystectomy	34
Small bowel partial resection	27
Total gastrectomy	5
Sub-total gastrectomy	3
Distal pancreatectomy	6
Rigth upper quadrant peritonectomy	47
Left upper quadrant peritonectomy	38
Pelvic peritonectomy	43

Table 2 Association between morbidity and clinical variables n (%)

Variable	No. of cases	With complications	Without complications	P-value
Gender				NS
Male	23	11 (46)	12 (41)
Female	30	13 (54)	17 (59)
Age (yr)		59 ± 10	56 ± 9	NS
Body mass index (Kg/m2)		25.4 ± 5.3	26.8 ± 4.7	NS
Previous systemic chemotherapy				NS
Performed	21	10 (42)	11 (38)
Not performed	32	14 (58)	18 (62)
PCI				NS
> 16	36	18 (75)	18 (62)
< 16	17	6 (25)	11 (38)
Operative time (h)		8.5 ± 3.0	7.1 ± 2.1	NS
Completeness of cancer resection				0.017
CCR-0	35	12 (50)	23 (79)
CCR-1	18	12 (50)	6 (21)

Table 3 Postoperative complications observed in 24 patients. Multiple complications are included

Complication	No. of cases	Treatment (No. of cases)
Surgical
Wound infection	4	Drainage
Urinary tract perforation	2	Reoperation (1); Urinary stenting (1)
Intestinal fistula	3	Reoperation
Abdominal abscess	2	US-guided drainage (1); medical (1)
Prolonged ileous	1	Medical
Bleeding from gastric ulcer	1	Endoscopic haemostasis
Intraabdominal bleeding	2	Reoperation
abdominal wall dehiscence	1	Conservative
Medical
Grade ≥ 2 hematological toxicity	3	Medical
Acute renal failure	1	Medical
Arrhythmias	1	Medical
Cutaneous rush	1	Medical
Sepsis	2	Medical