MYC and gastric adenocarcinoma carcinogenesis

Table 1 Several MYC studies in gastric cancer

Reference	Cause of MYC deregulation	Increased MYC	Number of cases	Rate (%) of cases with MYC deregulation
[38]	Overexpression	Protein	88	55
[39]	Overexpression	Protein	213	23.5
[40]	Amplification/Overexpression	DNA/Protein	31/51	12.9/41.2
[41]	Overexpression	RNA	51	68.6
[42]	Amplification	DNA	23	26
[43]	Amplification	DNA	21	48
[44]	Amplification	Protein	154	15.5
[45]	Overexpression	Protein	48 advanced/28 early	50/42
[46]	Overexpression	Protein	98 advanced/45 early	28/34
[47]	Amplification	DNA	51	24
[48]	Amplification	DNA	10	30
[49]	Overexpression	Protein	42 advanced/77 early	40.5/15.6
[50]	Amplification/Overexpression	DNA/Protein	23	26
[51]	Overexpression	Protein	30 advanced/ 6 early	63.3/50
[52]	Overexpression	Protein	35 advanced/74 early	34/16
[53]	Overexpression	Protein	84	88.1
[54]	Overexpression	Protein	63	52.4
[55]	Overexpression	Protein	65	61.5
[56]	Amplification	DNA/Protein	11	100
[37]	Amplification/Overexpression	DNA/Protein	7	100
[57]	Overexpression	Protein	204	43
[58]	Overexpression	Protein	71	42.3
[59]	Amplification/Overexpression	DNA/Protein	5 early	100