Expression of phosphatase and tensin homolog deleted on chromosome ten in liver of athymic mice with hepatocellular carcinoma and the effect of Fuzheng Jiedu Decoction

Table 1 Survival time in different groups

Group	n	Survival days	Survival rate (%)
		mean ± SD	3 wk	4 wk
A	12	23.67 ± 4.92	10/12 (83.3)	5/12 (41.7)
B	12	26.08 ± 2.31	12/12 (100)a	6/12 (50)a
C	12	25.92 ± 2.71	12/12 (100)a	7/12 (58.3)b
D	12	18.83 ± 2.29	7/12 (58.3)	0/12 (0)

^aP < 0.05,

^bP < 0.01 vs group D.

Table 2 Volume and index of tumors (mean ± SD)

Group	n	Volume (mm3)	Index
A	12	466.43 ± 645.66	0.0037 ± 0.0403
B	12	215.91 ± 275.23	0.0305 ± 0.0403
C	12	325.23 ± 464.30	0.0313 ± 0.0436
D	12	309.7 ± 309.72	0.0462 ± 0.0296

Table 3 Tumor metastasis in livers

Group	Rate of tumor metastasis in liver (%)
A + B + C	23/36 (63.9)a
A	7/12 (58.3)c
B	9/12 (75)
C	7/12(58.3)c
D	12/12(100)

^aP < 0.05 vs group D;

^cP < 0.05 vs group D.

Table 4 Expression intensity of PTEN in the 3 kinds of tissue (α= 0.01)

Kind of tissue	n	PTEN intensity median
Normal hepatic tissue	48	1.00
Latero-cancer tissue	48	1.31
Cancer tissue	48	0.23

Table 5 Expression intensity of PTEN of 3 kinds of tissue of the 4 groups (mean ± SD)

Group	n	Normal hepatic tissue	Latero-cancer tissue	Cancer tissue(median)
A	12	1.05 ± 0.34	1.42 ± 0.24	0.36
B	12	0.90 ± 0.31	1.75 ± 0.42	0.86
C	12	1.06 ± 0.18	1.27 ± 0.21	0.20
D	12	0.59 ± 0.48	0.64 ± 0.61	0.05