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World J Gastroenterol. Feb 21, 2007; 13(7): 1042-1052
Published online Feb 21, 2007. doi: 10.3748/wjg.v13.i7.1042
Published online Feb 21, 2007. doi: 10.3748/wjg.v13.i7.1042
Parameter | Control | Iron deficient | Iron excess |
Ferritin (ng/mg protein) | |||
Lumen | 126.0a± 61.42 | 105.8a± 35.81 | 228.8c± 73.54 |
Mucosa | 308.3c± 123.36 | 256.0c± 1.19 | 731.5e± 191.96 |
Transferrin (μg/mg protein) | |||
Lumen | 10.9b± 7.6 | 11.1b± 10.3 | 6.8b± 4.7 |
Mucosa | 0.87d± 0.79 | 0.80d± 1.20 | 0.61d± 0.63 |
Radioactiveiron/protein | Iron status | Basal | 5 min | 15 min | 30 min | 2h |
59Fe | ID | - | SUR+ | IE+++ | IE+++ | - |
OL | - | SUR+++ | IE± | IE± | - | |
Tf | ID | IV± | IV++ | IE+++ | IE+ | |
IV++ | IV++ | |||||
OL | IV± | IE± | IE± | |||
IV± | IV± | |||||
TfR | ID | SUR± | SUR++ | IE++ | IE+ | SUR± |
OL | SUR± | SUR++ | SUR+ | - | - | |
Fe | ID | IE± | IE± | |||
IV± | - | - | ||||
OL | IE± | - | IE± | IE± | ||
IV+++ |
Sex | No | Age (yr) | Hb (g/dL) | PCV | RBC M/cu mm | Serum ferritin (μg/L) | |
Normal | M | 12 | 36.5 ± 10.6 | 14.8 ± 0.9 | 44.5 ± 3.3 | 5.8 ± 0.7 | 43 ± 22.1 |
F | 1 | 7.2 | 12.4 | 36 | 4.5 | 71.7 | |
Iron deficient anemia | M | 4 | 24.5 ± 20.9 | 7.4 ± 2.6 | 23.3 ± 9.0 | 4.1 ± 1.7 | 7.2 ± 4.0 |
F | 2 | 20.5 | 7.3 | 26.5 | 3.5 | 6.5 | |
M | 10 | 44.3 ± 16.5 | 11.1 ± 1.64 | 33.6 ± 5.2 | 4.5 ± 1.4 | 75.3 ± 32.2 | |
Anemia | F | 4 | 21 ± 6.6 | 6.8 ± 3.0 | 20.8 ± 9.0 | 2.1 ± 1.2 | 57.4 ± 13.4 |
Iron supplements | F | ||||||
Blood transfusion | M | 1 | 32 | 9.5 | 29 | 4.7 | 28.6 |
Iron injection | F | 1 | 32 | 8.4 | 27 | 4.3 | 101 |
Oral iron | F | 1 | 20 | 9.7 | 30 | 3 | 38 |
- Citation: Kolachala VL, Sesikeran B, Nair KM. Evidence for a sequential transfer of iron amongst ferritin, transferrin and transferrin receptor during duodenal absorption of iron in rat and human. World J Gastroenterol 2007; 13(7): 1042-1052
- URL: https://www.wjgnet.com/1007-9327/full/v13/i7/1042.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i7.1042