Chromosome 11 aneusomy in esophageal cancers and precancerous lesions- an early event in neoplastic transformation: An interphase fluorescence in situ hybridization study from south India

Table 1 Details of cases analyzed for chromosome 11 aneusomy using FISH in different esophageal pathologies and controls

Case, No.	Case type	Details	Chromosome 11 % aneusomy
			Trisomy (%)	Tetrasomy (%)	Pentasomy (%)
1	Controls	Normal	-	-	-
2		Normal	-	-	-
3		Normal	-	-	-
4		Normal	-	-	-
5		Normal	-	-	-
6	Precancers	Sq. dysplasia (High grade)	4.0	-	-
7		Sq. dysplasia (High grade)	10.0	0.4	-
8		Barrett's dysplasia (High grade)	15.2	2.4	0.8
9		Barrett's dysplasia (High grade)	5.6	-	-
10	Cancers	ADC	12.8	2.0	-
11		ADC	10.0	2.0	-
12		WDSCC	11.2	-	-
13		WDSCC	12.8	0.4	-
14		WDSCC	8.8	2.4	-
15		MDSCC	10.0	0.8	-
16		MDSCC	12.8	0.4	0.4
17		MDSCC	5.2	0.8	-
18		PDSCC	1.6	-	-
19		PDSCC	6.0	-	-
20		PDSCC	3.2	-	-

Percentage of aneusomy in different cases from the first 250 cells scored. (Monosomies and normal disomies are not shown in the table). ADC: Adenocarcinoma; WDSCC: Well differentiated SCC; MDSCC: Moderately differentiated SCC; PDSCC: Poorly differentiated SCC; Sq. : Squamous.