Wu SK, Wang BJ, Yang Y, Feng XH, Zhao XP, Yang DL. Expression of PTEN, PPM1A and P-Smad2 in hepatocellular carcinomas and adjacent liver tissues. World J Gastroenterol 2007; 13(34): 4554-4559 [PMID: 17729405 DOI: 10.3748/wjg.v13.i34.4554]
Corresponding Author of This Article
Dr. Dong-Liang Yang, Division of Clinical Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095# Jiefangdadao, Wuhan 430030, Hubei Province, China. dlyang@tjh.tjmu.edu.cn Telephone: +86-27-83662894 Fax: +86-27-83662894
Article-Type of This Article
Liver Cancer
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Table 4 Relationship of PTEN, PPM1A and P-Smad2 with HCC, paracancerous and non-tumor liver tissues
Types
Cases (n)
PTEN
PPM1A
P-Smad2
Cytoplasm
Nucleus
Cytoplasm
Nucleus
Cytoplasm
Nucleus
HCC
31
20
0
26
20
8
31
Paracancerous tissue
25
24
17
7
25
25
25
Non-tumor liver tissue
13
13
12
0
13
11
13
Table 5 Relationship of PPM1A and P-Smad2 with different Edmondson grades of HCC
Pathological type
Cases (n)
PPM1A
P-Smad2
Cytoplasm
Nucleus
Cytoplasm
Nucleus
HCC (Edmondson grade)
31
26
20
8
31
GradeIandI-II
10
5
9
7
10
Grade II
7
7
6
1
7
Grade II-III and above
14
14
5
0
14
Citation: Wu SK, Wang BJ, Yang Y, Feng XH, Zhao XP, Yang DL. Expression of PTEN, PPM1A and P-Smad2 in hepatocellular carcinomas and adjacent liver tissues. World J Gastroenterol 2007; 13(34): 4554-4559