Glutathione-S-transferase M1 polymorphisms on the susceptibility to esophageal cancer among three Chinese minorities: Kazakh, Tajik and Uygur

Table 1 Frequencies of GSTM1 polymorphisms in three ethnics

Ethnic	GSTM1		OR (95% CI)	P
	Null [n (%)]	Present [n (%)]
Kazakh
Male	130 (48.33)	139 (51.67)
Female	180 (46.75)	205 (53.25)
Total	310 (47.40)	344 (52.60)
			11.859 (1.445-2.391)	0.000
Uygur
Male	99 (67.81)	47 (32.19)
Female	159 (59.77)	107 (40.23)
Total	258 (62.63)	154 (37.37)
			20.619 (0.352-1.809)	0.106
Tajik
Male	13 (50.00)	13 (50.00)
Female	15 (51.72)	14 (48.28)
Total	28 (50.91)	27 (49.09)
			31.151 (0.664-1.996)	0.674

OR: odds ratio; CI: confidence interval.

¹Kazakh vs Uygur;

²Uygur vs Tajik;

³Kazakh vs Tajik.

Table 2 Correlation of clinicopathological grade of EC with GSTM1 genotypes in Kazakh

ESCC grade	GSTM1		OR (95% CI)	P
	Null [n (%)]	Present [n (%)]
High	12 (23.53)	39 (76.47 )
Low	32 (49.23)	33 (50.77)	3.152 (1.403-7.080)	0.007