Expression of 5-Lipoxygenase in human colorectal cancer

Table 1 Correlation of clinicopathologic parameters with 5-Lox mRNA expression

Clinicopathologicparameters	n	5- Lox expression		P
		Low	High
All cases:	91	25 (27.47%)	66 (72.53%)
Age:	91	Rho = 0.018		NS1
Gender:
Male	53	15	38
Female	38	10	28	NS
Tumor site:
Colon	49	13	36
Rectum	42	12	30	NS
Tumor size:	91	Rho = 0.392		0.00021
Histology:
Well	49	11	38
Moderate	34	13	21
Poor	8	1	7	NS
Depth of invasion:
pT1	11	7	4
pT2	18	6	12
pT3	43	9	34
pT4	19	3	16	0.021
Lymph node metastasis:
Yes	45	16	29
No	46	9	37	NS
Lymphatic invasion:
Yes	66	14	52
No	25	11	14	0.030
Venous invasion:
Yes	72	15	57
No	19	10	9	0.006
TNM stage:
I	12	2	10
II	31	7	24
III	38	15	23
IV	10	1	9	NS

¹Spearman rank test P value; NS: Not Significant (P > 0.05).