Expression of insulin-like growth factor binding protein-2 in gastric carcinoma and its relationship with cell proliferation

Table 1 Clinical and pathological characteristics of patients with early gastric carcinoma (n = 118)

Characteristic	n
All patients	118
Gender
Male/Female	71/47
Age (yr)
Median (Range)	53.2 (24-76)
Tumor site
Cardia	21
Fundus/body	43
Antrum	54
Histological type
Differentiated	56
Undifferentiated	62
Lymph node metastasis
Positive	67
Negative	51
pTNM stage
I-II	52
III-IV	66
Depth wall penetration
T1-T2	48
T3-T4	70

Table 2 Quantitative score of IGFBP2 expression in normal gastric mucosa and gastric carcinoma

Group	Quantitative score of IGFBP2 expression	P
	(mean ± SD)
Normal mucosa	1.06 ± 0.64	< 0.01
Carcinoma	2.61 ± 0.94

Table 3 Summary of quantitative score of IGFBP2 expression in gastric carcinoma according to clinical and pathological parameters (mean ± SD)

Parameter	Quantitative score ofIGFBP2 expression	P
Gender Male Female	2.05 ± 0.82 2.35 ± 0.81	> 0.05
Tumor site Cardia Fundus/body Antrum	2.19 ± 0.98 2.31 ± 0.89 2.18 ± 0.95	> 0.05
Histological type Differentiated Undifferentiated	2.31 ± 0.82 2.72 ± 0.88	> 0.05
Lymph node metastasis Positive Negative	2.16 ± 0.98 2.81 ± 0.91	< 0.01
pTNM stage I-II III-IV	2.02 ± 0.93 2.98 ± 0.87	< 0.01
Depth wall penetration T1-T2 T3-T4	2.08 ± 0.97 2.79 ± 0.84	< 0.05