Efficacy of ultrasonography and alpha-fetoprotein on early detection of hepatocellular carcinoma

Table 1 Comparison of liver status at initial screening and detection of HCC

Liver status	Patients, n (%)
	At initial screening	At detection of HCC
CH	63 (23.9)	9 (3.4)
LC	201 (76.1)	255 (96.6)
Child A	85 (42.2)	122 (47.8)
Child B	38 (19.0)	58 (22.7)
Child C	78 (14.9)	75 (26.1)

Table 2 Underlying liver diseases at initial US of patients with HCC, n (%)

Liver status	HBV (+)	HCV (+)	BC	NBNC	Total
CH	45 (17.3)	13 (4.9)	3 (1.1)	3 (0.6)	42 (23.5)
LC	145 (54.8)	37 (14.0)	2 (0.9)	17 (6.4)	201 (76.1)
Total	190 (72.1)	50 (18.9)	5 (2.0)	19 (7.0)	264 (100.0)

Table 3 Tumor size at diagnosis

Diameter (cm)	Patients, n (%)
≤ 2	106 (40.8)
> 2-3	70 (26.9)
> 3-5	57 (21.9)
> 5	27 (10.4)
Total	260 (100.0)

Table 4 Tumor size according to US interval

US interval (mo)	Patients, n (%)	Tumor size (cm)
≤ 6	124 (47.2)	2.7 ± 1.3a
≤ 3	26 (10.0)	3.4 ± 1.8
4-6	98 (37.2)	2.5 ± 1.1
> 6	140 (52.8)	3.4 ± 2.0
7-12	90 (34.0)	3.0 ± 2.1
> 12	50 (18.8)	4.4 ± 1.7
Total	264 (100.0)	3.1 ± 1.7

^aP < 0.01 vs > 6-mo group.

Table 5 Median survival according to tumor size

Diameter	Patients, n (%)	Median survival (mo)
≤ 2	106 (40.8)	42
> 2-3	70 (26.9)	35
> 3-5	57 (21.9)	20
> 5	26 (10.4)	10
Total	260 (100.0)	31

Table 6 Serum AFP level at detection of HCC

AFP level (ng/mL)	Patients, n (%)
≤ 20	107 (41.1)
≥ 1-400	86 (29.6)
> 400	70 (29.3)