Mistletoe alkali inhibits peroxidation in rat liver and kidney

Table 1 LPO, GSH- Px, SOD in rat liver (n = 32, mean ± SD)

Groups	Dosage	LPO	GSH-Px	SOD
	(mg/kg)	(nmoL/mg protein)	(nmoL/mg protein)	(nmoL/mg protein)
Normal control	-	11.142 ± 0.916b	18.713 ± 3. 587b	31.537 ± 2.848b
CCl4 + MA group	90	10.326 ± 1.213b	20.403 ± 2.388c	39.901 ± 2.667c
CCl4 + vit E group	400	11.221 ± 2.182b	16.353 ± 2.962b	27.736 ± 3.646b
CCl4 group	-	17.271 ± 1.108	13.342 ± 3.636	21.639 ± 3.991

^bP < 0.01, ^cP < 0.05 vs CCl₄ group.

Table 2 LPO, GSH- Px, SOD in rat kidney (n = 32, mean ± SD)

Groups	dosage	LPO	GSH-Px	SOD
	( mg/kg)	(nmol/mgprotein)	(μ/g mL)	(μ/mg protein)
Normal control	-	1.268 ± 0.99b	7.174 ± 0.576c	39.573 ± 7.322c
CCl4 + MA group	90	1.973 ± 0.512b	7.431 ± 0.483c	37.887 ± 6.979b
CCl4 + Vit E group	400	1.312 ± 0.418b	6.698 ± 0.746b	39.399 ± 8. 684c
CCl4 group	-	3.826 ± 0.289	4.576 ± 0.611	22.639 ± 5.342

^bP < 0.01,

^cP < 0.05 vs CCl₄ group.

Table 3 MDA, SOD, GSH- Px in blood plasma (n = 32, mean ± SD)

Groups	Dosage	MDA	GSH-Px	SOD
	(g/kg)	(mol/L)	(μ/mL)	(μ/mL)
Norma control	-	14.341 ± 2.01	21.17 ± 3.82b	19.01 ± 2.36b
CCl4 + MA group	90	12.88 ± 3.98b	22.67 ± 3.42b	23.62 ± 3.17c
CCl4 + Vit E group	400	14.91 ± 2.79	18.77 ± 1.98b	17.63 ± 1.88b
CCl4 group	-	14.98 ± 3.63	16.11 ± 2.41	14.88 ± 3.15

^bP < 0.01,

^cP < 0.05 vs CCl₄ group.

Table 4 Effects of mistletoe alkali on Fenton and H₂O₂/UV-mediated DMPO-OH formation

Drug concentration (μg/ mL)	Sample size (n)	Opposite high peak of ESR (mean ± SD)	Clearance rate (%)
0	20	38.71 ± 3.62	_
2	20	34.16 ± 3.75	11.67
10	20	29.42 ± 2.99	47.82
50	20	22.65 ± 4.83	67.67
100	20	14.38 ± 2.76	91.28