Malnutrition affects quality of life in gastroenterology patients

Table 1 Clinical diagnoses of the study population

Diagnoses	n		n		n
Liver cirrhosis	61	Others	70
Alcoholic liver cirrhosis	51	Biliary disease	11	Functional dyspepsia/IBS	4
Cryptogenic liver cirrhosis	4	Gastritis / reflux disease	11	Ulcer disease	3
Biliary liver cirrhosis	4	Chronic pancreatitis	9	Colon and/or rectal polyps	2
Post hepatic liver cirrhosis	2	Non infectious colitis	7	Malabsorption syndrome	2
Inflammatory bowel disease	69	Diverticulitis	8	Viral hepatitis	2
Crohn’s disease	46	Fatty liver disease	8	Proctologic disease	2
Ulcerative colitis	23			Total	200

Table 2 Study population and differences between well and malnourished patients

Characteristics	Overall study population(n = 200)	Well nourished (SGA A)(n = 104)	Malnourished (SGA B C)(n = 96)	P
Gender (M/F)	94/106	44/60	50/46	NS
Age (yr)	54.9 ± 17.1	56.7 ± 16.7	52.9 ± 17.3	NS
Albumin (g/L)	37 ± 7.1	39 ± 7.0	35 ± 7.0	0.001
Body mass index (kg/m²)	23.7 ± 4.9	25.7 ± 4.6	21.6 ± 4.2	<0.000
Phase angle (°)	4.9 ± 1.1	5.2 ± 1.0	4.5 ± 1.1	<0.000
BCM/height (kg/m²)	8.1 ± 1.8	8.6 ± 1.7	7.4 ± 1.8	<0.000
ECM/BCM	1.3 ± 0.6	1.2 ± .4	1.4 ± .7	<0.000
Arm muscle area (mm²)	4327.5 ± 1261.8	4713.2 ± 1200.3	3916.1 ± 1200.1	<0.000
Hand grip strength (kg)	29.1 ± 11.0	30.6 ± 10.5	27.3 ± 11.4	0.030
Peak flow (L/min)	346.0 ± 118.4	353.4 ± 113.2	337.6 ± 124.2	NS

Table 3 Study population and differences between liver cirrhosis and IBD patients

Differences	Liver cirrhosis	Inflammatorybowel disease	P
SGA A vs BC	34/27	33/36	NS
Gender (M/F)	33/28	29/40	NS
Age (yr)	56.8 ± 12.2	38.5 ± 13.4	< 0.000
Albumin (g/Ll)	33.0 ± 6.0	38.0 ± 7.0	< 0.000
Body mass index (kg/m²)	26.1 ± 4.9	21.2 ± 3.6	< 0.000
Phase angle (°)	4.7 ± 1.0	5.4 ± 1.2	< 0.000
BCM/height (kg/m²)	8.4 ± 1.9	7.9 ± 1.8	NS
ECM/BCM	1.4 ± .5	1.2 ± .8	< 0.000
Arm muscle area (mm²)	4606.3 ± 1485.9	3921.9 ± 1069.8	0.009
Hand grip strength (kg)	30.9 ± 11.6	31.5 ± 11.4	NS
Peak flow (L/min)	328.2 ± 116.9	375.8 ± 112.5	0.048

Table 4 Quality of life in malnourished vs wellnourished patients with either liver cirrhosis or inflammatory bowel disease (absolute percentage)

QOL scales	Liver cirrhosis			Inflammatory bowel disease
	Wellnourished	Malnourished	P	Wellnourished	Malnourished	P
Physical functioning	74.0 ± 23.8	44.6 ± 22.1	0.000	66.6 ± 31.6	52.1 ± 28.4	0.036
Role physical	52.3 ± 42.6	22.2 ± 36.9	0.003	49.2 ± 45.1	24.4 ± 34.6	0.024
Bodily pain	88.9 ± 28.5	59.3 ± 47.4	0.007	67.7 ± 41.9	59.1 ± 46.5	NS
General health	82.6 ± 27.4	81.0 ± 28.7	NS	71.9 ± 31.6	51.1 ± 33.1	0.012
Vitality	73.2 ± 38.2	59.0 ± 39.4	NS	35.4 ± 33.5	37.7 ± 33.7	NS
Social functioning	51.8 ± 19.8	41.3 ± 16.1	0.041	42.1 ± 20.2	37.6 ± 13.5	NS
Role emotional	46.8 ± 21.3	31.7 ± 20.0	0.007	39.1 ± 23.7	26.9 ± 18.8	0.027
Mental health	78.1 ± 17.6	56.9 ± 25.9	0.001	64.9 ± 18.9	56.1 ± 21.8	NS