Effects of adenovirus-mediated human cyclooxygenase-2 antisense RNA on the growth of hepatocellular carcinoma

Table 1 Relationship between high expression of COX-2 and clinical pathological features of liver cancer (mean+SD)

Clinical pathologicalfeatures	n	Stain fraction	t	P
AFP (ng/mL)
<20	4	6.48+1.46	0.74	>0.05
≥20	24	6.36+1.15
Cell category
Liver cell category	27	6.79+1.60
Bile duct cell category	1	6.26+1.25
Transference in liver
Yes	3	6.43+1.42	1.08	<0.05
No	25	7.15+1.80
Pathological differentiation
High	22	8.25+0.86	5.23	<0.05
Middle and low	6	6.11+102

Table 2 Cell apoptosis rate and cell cycle after SMMC7402 was treated in experimental group and control group (n = 9, mean+SD)

Groups	Apoptosis rate	Cell cycle (%)
	(%)	G0/G1	S	G2/M
Control group	0.25	40.39+3.86	49.61+4.27	13.10+1.03
Ad-LacZ	0.42	40.17+4.03	50.18+3.66	12.57+2.85
Ad-ASHcox-2	33.3	66.52+5.48	22.15+3.26	10.33+1.12

Table 3 Cell apoptosis rate and cell cycle after SMMC7721 was treated in experimental group and control group (mean+SD)

Groups	Apoptosis rate	Cell cycle (%)
	(%)	G0/G1	S	G2/M
Control group	0.56	40.39+3.86	49.61+4.27	13.10+1.03
Ad-LacZ	0.48	42.17+2.63	50.26+2.85	12.27+2.72
Ad-ASHcox-2	0.91	39.92+4.11	49.28+4.13	12.64+1.25