Levels of v5 and v6 CD44 splice variants in serum of patients with colorectal cancer are not correlated with pT stage, histopathological grade of malignancy and clinical features

Table 1 Sex of patients, grade of malignancy (G) and pT stage

	Inoperable tumours	G2 pT2	G2 pT3	G2 pT4	G3 pT3	G3 pT4	All
Women	4	4	23	5	10	0	46
	33.33%	44.44%	40.35%	41.67%	52.63%	0.00%	40.35%
Men	8	5	34	7	9	5	68
	66.67%	55.56%	59.65%	58.33%	47.37%	100.00%	59.65%
All	12	9	57	12	19	5	114
	10.53%	7.89%	50.00%	10.53%	16.67%	4.39%	100.00%

Table 2 Location of tumour, grade of malignancy (G) and pT stage

	Inoperable tumours	G2pT2	G2pT3	G2pT4	G3pT3	G3pT4	All
Sigmoid and rectum	6	4	34	6	7	2	59
	59.00%	44.44%	59.65%	50.00%	36.84%	40.00%	51.75%
Colon	6	5	23	6	12	3	55
	50.00%	55.56%	40.35%	50.00%	63.16%	60.00%	48.25%
All	12	9	57	12	19	5	114
	10.53%	7.89%	50.00%	10.53%	16.67%	4.39%	100.00%

Table 3 Mortality, grade of malignancy (G) and pT stage

	Inoperable tumours	G2pT2	G2pT3	G2pT4	G3pT3	G3pT4	All
Alive	1	8	48	11	12	3	83
	8.33%	88.89%	84.21%	91.67%	63.16%	60.00%	72.81%
Dead	11	1	9	1	7	2	31
	91.67%	11.11%	15.79%	8.38%	36.84%	40.00%	27.19%
All	12	9	57	12	19	5	114
	10.53%	7.89%	50.00%	10.53%	16.67%	4.39%	100.00%

Table 4 Mean values of CD44 v5 and CD44 v6 before and after operation (ng/ml)

		v5 A	v5 B	v6 A	v6 B
Age:	< 65	28.38	26.50	185.42	171.52
	> 65	25.18	27.61	178.78	183.18
Location:	the sigmoid and the rectum	24.92	30.08	173.26	178.15
	the colon	29.38	25.28	192.17	186.04
Inoperable tumours		29.88	25.92	178.42	189.17
G2 pT2		24.47	25.01	184.49	177.44
G2 pT3		26.98	27.87	181.96	181.78
G2 pT4		32.72	28.85	153.63	165.09
G3 pT3		23.21	23.76	181.74	183.00
G3 pT4		25.14	23.28	142.00	164.80