Effects of Radix Puerariae flavones on liver lipid metabolism in ovariectomized rats

doi:10.3748/wjg.v10.i13.1967

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Jul 1, 2004 (publication date) through Nov 30, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 1, 2004; 10(13): 1967-1970
Published online Jul 1, 2004. doi: 10.3748/wjg.v10.i13.1967

Table 1 Effect of RPF on body mass of OVX rats

Group	n	Body mass after	Body weight during	Wk 1 (g)	Wk 2 (g)	Wk 3 (g)	Wk 4 (g)	Wk 5 (g)	Change rate
Group	n	operation (g)	recovery period (g)	Wk 1 (g)	Wk 2 (g)	Wk 3 (g)	Wk 4 (g)	Wk 5 (g)	Change rate
OVX	8	215 ± 15	233 ± 17	250 ± 16	266 ± 16^c	276 ± 15^c	284 ± 16^c	268 ± 20^c	22.1%
Sham OVX	9	235 ± 4.7	230 ± 4	232 ± 7	235 ± 6	241 ± 9	246 ± 11	237 ± 14	7.1%
OVX + estrogen	10	236 ± 17	242.4 ± 21	249 ± 18	248 ± 16^a	239 ± 14^a	248 ± 18^a	239 ± 19^a	1.1%
OVX + RPF	10	216 ± 15	233.3 ± 16	243 ± 17	251 ± 20	249 ± 16^a	246 ± 19^a	245 ± 17^a	5.6%

Results expressed as mean ± SD.

^aP < 0.05 vs OVX group,

^cP < 0.05 vs sham-OVX.

Table 2 Effect of RPF on abdominal fat and fat factor of OVX rats

Group	n	Abdominal fat (g)	Compared with OVX (%)	Fat factor (%)	Compared with OVX (%)
OVX	8	13.2 ± 2.1^c	-	5.1 ± 0.4^c	-
Sham OVX	9	10.6 ± 3.2	80.4	4.6 ± 1.2	91.2
OVX + estrogen	10	6.8 ± 3.6^a	52.1	3.1 ± 1.6^a	60.1
OVX + RPF	10	8.5 ± 2.5^a	64.4	3.7 ± 1.2^a	72.1

Results expressed as mean ± SD.

^aP < 0.05 vs OVX group,

^cP < 0.05 vs sham-OVX.

Table 3 Effect of RPF on liver lipid metabolism of OVX rats

Group	n	TC (mg/dL)	Compared with OVX (%)	TG (mg/dL)	Compared with OVX (%)
OVX	8	16.4 ± 5.0^c	-	119 ± 26^c	-
Sham-OVX	9	11.4 ± 4.4	81 ± 27	65 ± 18	54 ± 15
OVX + estrogen	10	10.2 ± 1.7^a	62 ± 10	54 ± 31^a	45 ± 26
OVX + RPF	10	10.2 ± 2.0^a	76 ± 15	46 ± 24^a	39 ± 20

Results expressed as mean ± SD.

^aP < 0.05 vs OVX group,

^cP < 0.05 vs sham-OVX, OVX + estrogen and OVX + RPF group.

Table 4 Effect of RPF on wet uterus weight of OVX rats

Group	n	Uterus (g)	Uterus factor (‰)
OVX	8	0.11 ± 0.02^c	0.40 ± 0.10^c
Sham-OVX	9	0.39 ± 0.14	1.70 ± 0.60
OVX + estrogen	10	0.46 ± 0.34^a	2.10 ± 1.50^a
OVX + RPF	10	0.15 ± 0.03^a	0.70 ± 0.10^a

Results expressed as mean ± SD.

^aP < 0.05 vs OVX group,

^cP < 0.05 vs sham-OVX.

Citation: Wang JF, Guo YX, Niu JZ, Liu J, Wang LQ, Li PH. Effects of Radix Puerariae flavones on liver lipid metabolism in ovariectomized rats. World J Gastroenterol 2004; 10(13): 1967-1970
URL: https://www.wjgnet.com/1007-9327/full/v10/i13/1967.htm
DOI: https://dx.doi.org/10.3748/wjg.v10.i13.1967