Immunohistochemical study of lactate dehydrogenase isoenzymes in gastric cancer

Table 1 Staining intensity of LDH-5 and LDH-H in normal body mucosa and gastric body carcinoma

Grade	Surface epithelium		Parietal cells		Chief cells		Cancer cells
	LDH-5a	LDH-Hb	LDH-5a	LDH-Hb	LDH-5a	LDH-Hb	LDH-5a	LDH-Hb
-	16	10			7	2
±							3	7
+	10	6	7	1	20	14	7	4
++	1		15	6			10	5
+++			5	9			7
Total	27	16	27	16	27	16	27	16

^aP < 0.005,

^bP < 0.005. LDH: Lactate dehydrogenase.

Table 2 Staining intensity of LDH-5 and LDH-H in normal antral mucosa and gastric antral carcinoma

Grade	Surface epithelium		Pyloric glandular epithelium		Cancer cells
	LDH-5a	LDH-Hb	LDH-5a	LDH-Hb	LDH-5a	LDH-Hb
-	7	8	6	8		2
±					2	10
+	21	7	25	7	13	3
++	5		2		10
+++					8
Total	33	15	33	15	33	15

^aP < 0.005,

^bP > 0.75. LDH: Lactate dehydrogenase.

Table 3 Staining intensity of LDH-5 and LDH-H in normal antral mucosa, intestinal metaplasia and antral carcinoma

Grade	Glandular epithelium		Intestinal metaplastic epithelium		Cancer cells
	LDH-5a	LDH-Hb	LDH-5a	LDH-Hb	LDH-5a	LDH-Hb
-	2	5				1
±				1	1	6
+	10	4	7	4	6	2
++			4	4	4
+++			1		1
Total	12	9	12	9	12	9

^aP < 0.025,

^bP < 0.01. LDH: Lactate dehydrogenase.

Table 4 Staining intensity of LDH-5 and LDH-H in normal antral mucosa, dysplasia and antral carcinoma

Grade	Glandular epithelium		Dysplastic epithelium		Antral cancer cells
	LDH-5a	LDH-Hb	LDH-5a	LDH-Hb	LDH-5a	LDH-Hb
-	2	5			1	2
±				1	2	7
+	13	5	9	5	6	1
++			5	5	3
+++			1		4
Total	15	10	15	10	15	10

^aP < 0.025,

^bP < 0.025. LDH: Lactate dehydrogenase.