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Contents Volume 31 Issue 14 April 14, 2025

Editorial

Immune therapies in intermediate-advanced unresectable hepatocellular carcinoma: Changing the therapeutic landscape

Arghya Samanta, Sagnik Biswas

World J Gastroenterol 31(14):103267. Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.103267

Abstract (431) | Core Tip (421) | Full Article (HTML) (1569) | Full Article (PDF)-370K (149) | Full Article with Cover (PDF)-653K (125) | Full Article (XML)-68K (92) | Audio-1473K (30) | Peer-Review Report-251K (90) | Answering Reviewers-147K (92) | Received: 11/13/2024 | Revised: 03/13/2025 | Accepted: 03/19/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (4743) | Similar Articles (0) | Timeline of Article Publication (8) | Authors Evaluation (5) | Article Quality Tracking (0) | Cite |

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Guidelines

Clinical settings in which human leukocyte antigen typing is still useful in the diagnosis of celiac disease

Enrico Schirru, Rossano Rossino, Rita D Jores, Mara Corpino, Sandro Muntoni, Francesco Cucca, Mauro Congia

World J Gastroenterol 31(14):104397. Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.104397

Abstract (406) | Core Tip (430) | Full Article (HTML) (1777) | Figures (1-1) (337) | Tables (1-3) (342) | Full Article (PDF)-577K (170) | Full Article with Cover (PDF)-860K (166) | Full Article (XML)-214K (83) | Audio-600K (18) | Peer-Review Report-232K (85) | Answering Reviewers-205K (133) | Received: 12/18/2024 | Revised: 02/01/2025 | Accepted: 03/21/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (5760) | Similar Articles (147) | Timeline of Article Publication (5) | Article Quality Tracking (0) | Cite |

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Review

Interplay of genetic and clinical factors in cancer-associated thrombosis: Deciphering the prothrombotic landscape of colorectal cancer

Duo-Gang Xu, Jing Tan

World J Gastroenterol 31(14):103901. Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.103901

Abstract (405) | Core Tip (408) | Full Article (HTML) (2101) | Figures (1-4) (450) | Full Article (PDF)-3920K (176) | Full Article with Cover (PDF)-4203K (176) | Full Article (XML)-252K (91) | Audio-216K (40) | Peer-Review Report-299K (80) | Answering Reviewers-307K (91) | Supplementary Material-1350K (142) | Received: 12/03/2024 | Revised: 03/03/2025 | Accepted: 03/25/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (6111) | Similar Articles (1) | Timeline of Article Publication (6) | Authors Evaluation (5) | Article Quality Tracking (0) | Cite |

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Retrospective Cohort Study

Rapid pathologic grading-based diagnosis of esophageal squamous cell carcinoma via Raman spectroscopy and a deep learning algorithm

Xin-Ying Yu, Jian Chen, Lian-Yu Li, Feng-En Chen, Qiang He

World J Gastroenterol 31(14):104280. Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.104280

Abstract (443) | Core Tip (417) | Full Article (HTML) (1593) | Figures (1-8) (353) | Tables (1-6) (304) | Full Article (PDF)-6322K (168) | Full Article with Cover (PDF)-6605K (149) | Full Article (XML)-144K (100) | Audio-264K (48) | Peer-Review Report-210K (118) | Answering Reviewers-114K (108) | Received: 12/16/2024 | Revised: 02/23/2025 | Accepted: 03/24/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (6395) | Similar Articles (5) | Timeline of Article Publication (4) | Authors Evaluation (4) | Article Quality Tracking (0) | Reader Comments (1) | Cite |

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Retrospective Study

Prognostic scoring system using inflammation- and nutrition-related biomarkers to predict prognosis in stage I-III colorectal cancer patients

Ke-Jin Li, Zi-Yi Zhang, Kuan Wang, Subinur Sulayman, Xiang-Yue Zeng, Juan Liu, Yi Chen, Ze-Liang Zhao

World J Gastroenterol 31(14):104588. Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.104588

Abstract (441) | Core Tip (436) | Full Article (HTML) (2006) | Figures (1-6) (363) | Tables (1-3) (306) | Full Article (PDF)-2276K (179) | Full Article with Cover (PDF)-2560K (156) | Full Article (XML)-138K (92) | Audio-141K (84) | Peer-Review Report-252K (95) | Answering Reviewers-473K (100) | Received: 12/24/2024 | Revised: 02/22/2025 | Accepted: 03/21/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (25) | Total Visits (6010) | Similar Articles (1583) | Timeline of Article Publication (7) | Authors Evaluation (5) | Article Quality Tracking (0) | Cite |

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Clinical Trials Study

Efficacy of recombinant human thrombopoietin in patients with acute-on-chronic liver failure and thrombocytopenia: A prospective, open-label study

Jing Liang, Li Jing, Xu Zhang, Fu-Shuang Ha, Feng-Hui Li, Jun-Qing Yan, Tao Wang, Fei Tang, Gang Liu

World J Gastroenterol 31(14):105004. Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.105004

Abstract (409) | Core Tip (492) | Full Article (HTML) (1622) | Figures (1-4) (361) | Tables (1-4) (345) | Full Article (PDF)-853K (157) | Full Article with Cover (PDF)-1137K (120) | Full Article (XML)-100K (97) | Audio-640K (31) | Peer-Review Report-218K (99) | Answering Reviewers-150K (74) | Received: 01/08/2025 | Revised: 02/24/2025 | Accepted: 03/24/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (5673) | Similar Articles (83) | Timeline of Article Publication (3) | Authors Evaluation (4) | Article Quality Tracking (0) | Cite |

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Observational Study

Study of the relationship between iron metabolism disorders and sepsis-associated liver injury: A prospective observational study

Tian-Wei Wang, Lu-Lu Zhou, Jing Yuan, Wen-Xin Zhou, Hao-Ran Wang, Ting-Ting Yu, Ji-Chao Zhai, Cheng-Bin Tang, Wei Jiang, Jiang-Quan Yu, Rui-Qiang Zheng, Hai-Long Yu, Jun Shao

World J Gastroenterol 31(14):104584. Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.104584

Abstract (423) | Core Tip (427) | Full Article (HTML) (1520) | Figures (1-2) (305) | Tables (1-5) (342) | Full Article (PDF)-678K (130) | Full Article with Cover (PDF)-963K (153) | Full Article (XML)-149K (108) | Audio-648K (53) | Peer-Review Report-242K (91) | Answering Reviewers-147K (101) | Received: 12/24/2024 | Revised: 02/17/2025 | Accepted: 03/25/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (5) | Total Visits (6614) | Similar Articles (172) | Timeline of Article Publication (4) | Authors Evaluation (5) | Article Quality Tracking (0) | Cite |

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Prospective Study

Efficacy of a novel artificial liver versatile plasma purification system in patients with acute-on-chronic liver failure

Zhong-Shang Dai, Min Zhang, Yuan-Ye Deng, Ning Zhou, Yi Tian

World J Gastroenterol 31(14):103892. Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.103892

Abstract (390) | Core Tip (442) | Full Article (HTML) (1645) | Figures (1-3) (350) | Tables (1-2) (322) | Full Article (PDF)-2927K (179) | Full Article with Cover (PDF)-3211K (145) | Full Article (XML)-100K (121) | Audio-826K (26) | Peer-Review Report-278K (126) | Answering Reviewers-350K (82) | Supplementary Material-65K (99) | Received: 12/04/2024 | Revised: 02/05/2025 | Accepted: 03/26/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (3) | Total Visits (5887) | Similar Articles (52) | Timeline of Article Publication (6) | Authors Evaluation (8) | Article Quality Tracking (0) | Reader Comments (1) | Cite |

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Basic Study

Extramural venous invasion in gastric cancer: 9.4T magnetic resonance imaging assessment and circular RNA functional analysis

Cai-Zhen Feng, Xin-Yi Gou, Yi-Qun Liu, Yu-Wei Xin, Yin-Li Zhang, Hui-Min Zhao, Sheng-Cai Wei, Nan Hong, Yi Wang, Jin Cheng

World J Gastroenterol 31(14):99897. Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.99897

Abstract (408) | Core Tip (475) | Full Article (HTML) (1485) | Figures (1-7) (333) | Tables (1-2) (351) | Full Article (PDF)-16488K (158) | Full Article with Cover (PDF)-16773K (176) | Full Article (XML)-109K (99) | Audio-1344K (16) | Peer-Review Report-206K (108) | Answering Reviewers-369K (102) | Received: 08/02/2024 | Revised: 02/19/2025 | Accepted: 03/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (5671) | Similar Articles (1539) | Timeline of Article Publication (3) | Authors Evaluation (4) | Article Quality Tracking (0) | Cite |

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Using vaporized hydrogen peroxide for anhydrous disinfection of gastrointestinal endoscopes

Can Zhao, Li-Hong Qi, Long-Song Li, Ying-Ying Wang, Ting Liang, Ning-Li Chai

World J Gastroenterol 31(14):103921. Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.103921

Abstract (409) | Core Tip (437) | Full Article (HTML) (1537) | Figures (1-6) (362) | Tables (1-5) (315) | Full Article (PDF)-6457K (181) | Full Article with Cover (PDF)-6738K (147) | Full Article (XML)-90K (93) | Audio-1333K (35) | Peer-Review Report-212K (83) | Answering Reviewers-106K (95) | Received: 12/04/2024 | Revised: 02/22/2025 | Accepted: 03/17/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (5145) | Similar Articles (0) | Timeline of Article Publication (10) | Authors Evaluation (5) | Article Quality Tracking (0) | Cite |

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Hepatic-specific vitamin D receptor downregulation alleviates aging-related metabolic dysfunction-associated steatotic liver disease

Feng Zhu, Bing-Ru Lin, Shi-Hua Lin, Chao-Hui Yu, Yun-Mei Yang

World J Gastroenterol 31(14):104117. Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.104117

Abstract (447) | Core Tip (399) | Full Article (HTML) (1678) | Figures (1-7) (349) | Full Article (PDF)-34673K (205) | Full Article with Cover (PDF)-34957K (188) | Full Article (XML)-144K (95) | Audio-192K (40) | Peer-Review Report-228K (83) | Answering Reviewers-442K (86) | Supplementary Material-562K (98) | Received: 12/10/2024 | Revised: 02/21/2025 | Accepted: 03/21/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (5396) | Similar Articles (125) | Timeline of Article Publication (3) | Article Quality Tracking (0) | Cite |

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Clinical, genetic and functional perspectives on ATP-binding cassette subfamily B member 4 variants in five cholestasis adults

Yu-Hang Weng, Yu-Feng Zheng, Dan-Dan Yin, Qing-Fang Xiong, Jin-Long Li, Shun-Xin Li, Wei Chen, Yong-Feng Yang

World J Gastroenterol 31(14):104975. Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.104975

Abstract (461) | Core Tip (416) | Full Article (HTML) (1163) | Figures (1-5) (351) | Tables (1-2) (348) | Full Article (PDF)-13088K (215) | Full Article with Cover (PDF)-13371K (116) | Full Article (XML)-140K (94) | Audio-11090K (22) | Peer-Review Report-221K (77) | Answering Reviewers-179K (85) | Supplementary Material-1176K (130) | Received: 01/07/2025 | Revised: 02/26/2025 | Accepted: 03/21/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (4838) | Similar Articles (53) | Timeline of Article Publication (4) | Authors Evaluation (5) | Article Quality Tracking (0) | Cite |

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Letter to the Editor

Chinese patent medicine: Opening new perspectives for treatment of post-endoscopic submucosal dissection esophageal stricture in esophageal cancer patients

Jie-Yu Guo, Xue-Ying Dong, Shi Li, Jing-Feng Tang, Ce-Fan Zhou

World J Gastroenterol 31(14):102943. Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.102943

Abstract (420) | Core Tip (442) | Full Article (HTML) (1397) | Full Article (PDF)-359K (117) | Full Article with Cover (PDF)-644K (115) | Full Article (XML)-55K (89) | Audio-232K (5) | Peer-Review Report-231K (88) | Answering Reviewers-92K (84) | Received: 11/02/2024 | Revised: 02/28/2025 | Accepted: 03/10/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (2) | Total Visits (3873) | Similar Articles (3) | Timeline of Article Publication (4) | Authors Evaluation (3) | Article Quality Tracking (0) | Cite |

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Mixed lineage kinase domain-like protein in liver diseases: Cell-type-specific functions and dual roles

Ming-Xing Liang, Ying Zhou, Su-Qun Li, Wan-Sheng Xiang, Zong-Qin Pan, Ying-Hua Chen, Yi-Huai He

World J Gastroenterol 31(14):104523. Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.104523

Abstract (400) | Core Tip (409) | Full Article (HTML) (1125) | Full Article (PDF)-428K (115) | Full Article with Cover (PDF)-713K (129) | Full Article (XML)-115K (85) | Audio-3220K (8) | Peer-Review Report-247K (79) | Answering Reviewers-99K (84) | Received: 12/23/2024 | Revised: 02/25/2025 | Accepted: 03/13/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (0) | Total Visits (3521) | Similar Articles (26) | Timeline of Article Publication (2) | Article Quality Tracking (0) | Cite |

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Gut microbiota plays a key role in the development of colorectal cancer

Ying-Ling Liu, Jie Liu

World J Gastroenterol 31(14):105420. Published online Apr 14, 2025. doi: 10.3748/wjg.v31.i14.105420

Abstract (433) | Core Tip (433) | Full Article (HTML) (1625) | Full Article (PDF)-373K (132) | Full Article with Cover (PDF)-658K (146) | Full Article (XML)-78K (91) | Audio-655K (12) | Peer-Review Report-222K (83) | Answering Reviewers-216K (91) | Received: 01/21/2025 | Revised: 03/05/2025 | Accepted: 03/10/2025 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (1) | Total Visits (4386) | Similar Articles (1283) | Timeline of Article Publication (2) | Article Quality Tracking (1) | Cite |

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