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Contents Volume 27 Issue 43 November 21, 2021

Frontier

Antimicrobial peptides and the gut microbiome in inflammatory bowel disease

John Gubatan, Derek R Holman, Christopher J Puntasecca, Danielle Polevoi, Samuel JS Rubin, Stephan Rogalla

World J Gastroenterol 27(43):7402-7422. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7402

Abstract (873) | Core Tip (1192) | Full Article (HTML) (7805) | Tables (1-3) (847) | Full Article (PDF)-875K (662) | Audio-924K (10) | Peer-Review Report-243K (123) | Answering Reviewers-402K (128) | Received: 03/19/2021 | Revised: 05/13/2021 | Accepted: 11/15/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (68) | Total Visits (15155) | Similar Articles (633) | Timeline of Article Publication (1) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Idiopathic chronic pancreatitis: Beyond antioxidants

Rajiv M Mehta, Stephen J Pandol, Prachi R Joshi

World J Gastroenterol 27(43):7423-7432. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7423

Abstract (1190) | Core Tip (818) | Full Article (HTML) (4075) | Figures (1-3) (430) | Full Article (PDF)-873K (412) | Audio-807K (4) | Peer-Review Report-196K (130) | Answering Reviewers-44K (132) | Received: 03/30/2021 | Revised: 07/05/2021 | Accepted: 10/27/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (6) | Total Visits (9662) | Similar Articles (98) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Opinion Review

COVID-19 as a trigger of irritable bowel syndrome: A review of potential mechanisms

Carlo Romano Settanni, Gianluca Ianiro, Francesca Romana Ponziani, Stefano Bibbò, Jonathan Philip Segal, Giovanni Cammarota, Antonio Gasbarrini

World J Gastroenterol 27(43):7433-7445. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7433

Abstract (938) | Core Tip (1255) | Full Article (HTML) (7576) | Figures (1-1) (745) | Full Article (PDF)-904K (886) | Audio-1199K (16) | Peer-Review Report-230K (216) | Answering Reviewers-122K (183) | Received: 03/04/2021 | Revised: 05/10/2021 | Accepted: 11/15/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (44) | Total Visits (15336) | Similar Articles (910) | Timeline of Article Publication (2) | Authors Evaluation (2) | Article Quality Tracking (3) | What about the content of this article? (0) | Cite |

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Review

Overview of the microbiota in the gut-liver axis in viral B and C hepatitis

Maria Adriana Neag, Andrei Otto Mitre, Adrian Catinean, Anca Dana Buzoianu

World J Gastroenterol 27(43):7446-7461. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7446

Abstract (870) | Core Tip (796) | Full Article (HTML) (4054) | Figures (1-2) (564) | Tables (1-2) (833) | Full Article (PDF)-1404K (474) | Audio-472K (10) | Peer-Review Report-304K (170) | Answering Reviewers-260K (144) | Received: 03/18/2021 | Revised: 08/13/2021 | Accepted: 11/03/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (13) | Total Visits (11423) | Similar Articles (7) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Hepatocellular carcinoma locoregional therapies: Outcomes and future horizons

Mina S Makary, Stuart Ramsell, Eric Miller, Eliza W Beal, Joshua D Dowell

World J Gastroenterol 27(43):7462-7479. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7462

Abstract (1181) | Core Tip (744) | Full Article (HTML) (4507) | Figures (1-1) (448) | Tables (1-2) (607) | Full Article (PDF)-946K (558) | Audio-1281K (8) | Peer-Review Report-143K (174) | Answering Reviewers-74K (155) | Received: 04/23/2021 | Revised: 07/09/2021 | Accepted: 10/27/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (45) | Total Visits (11294) | Similar Articles (1721) | Timeline of Article Publication (0) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Minireviews

Recent advances in artificial intelligence for pancreatic ductal adenocarcinoma

Hiromitsu Hayashi, Norio Uemura, Kazuki Matsumura, Liu Zhao, Hiroki Sato, Yuta Shiraishi, Yo-ichi Yamashita, Hideo Baba

World J Gastroenterol 27(43):7480-7496. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7480

Abstract (903) | Core Tip (838) | Full Article (HTML) (4460) | Figures (1-2) (471) | Tables (1-1) (494) | Full Article (PDF)-1564K (543) | Audio-1725K (7) | Peer-Review Report-342K (203) | Answering Reviewers-92K (148) | Supplementary Material-119K (177) | Received: 04/03/2021 | Revised: 08/02/2021 | Accepted: 11/15/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (21) | Total Visits (11934) | Similar Articles (261) | Timeline of Article Publication (0) | Authors Evaluation (2) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Hepatitis B: Who should be treated?-managing patients with chronic hepatitis B during the immune-tolerant and immunoactive phases

Miwa Kawanaka, Ken Nishino, Hirofumi Kawamoto, Ken Haruma

World J Gastroenterol 27(43):7497-7508. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7497

Abstract (815) | Core Tip (804) | Full Article (HTML) (3851) | Tables (1-3) (582) | Full Article (PDF)-783K (495) | Audio-1531K (7) | Peer-Review Report-221K (156) | Answering Reviewers-78K (141) | Received: 04/23/2021 | Revised: 07/31/2021 | Accepted: 10/31/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (15) | Total Visits (9136) | Similar Articles (180) | Timeline of Article Publication (5) | Article Quality Tracking (2) | What about the content of this article? (0) | Cite |

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Basic Study

Liver injury changes the biological characters of serum small extracellular vesicles and reprograms hepatic macrophages in mice

Xiu-Fang Lv, An-Qi Zhang, Wei-Qi Liu, Min Zhao, Jing Li, Li He, Li Cheng, Yu-Feng Sun, Gang Qin, Peng Lu, Yu-Hua Ji, Ju-Ling Ji

World J Gastroenterol 27(43):7509-7529. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7509

Abstract (961) | Core Tip (1002) | Article Highlights (716) | Full Article (HTML) (3083) | Figures (1-7) (755) | Tables (1-1) (411) | Full Article (PDF)-24863K (327) | Full Article (XML)-181K (66) | Audio-622K (8) | Peer-Review Report-201K (114) | Answering Reviewers-328K (118) | Supplementary Material-789K (215) | Received: 04/21/2021 | Revised: 07/21/2021 | Accepted: 09/16/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (5) | Total Visits (10340) | Similar Articles (105) | Timeline of Article Publication (8) | Authors Evaluation (4) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Genome-wide map of N⁶-methyladenosine circular RNAs identified in mice model of severe acute pancreatitis

Jun Wu, Xiao-Hui Yuan, Wen Jiang, Yi-Chen Lu, Qi-Lin Huang, Yi Yang, Hua-Ji Qie, Jiang-Tao Liu, Hong-Yu Sun, Li-Jun Tang

World J Gastroenterol 27(43):7530-7545. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7530

Abstract (796) | Core Tip (735) | Article Highlights (812) | Full Article (HTML) (3158) | Figures (1-8) (374) | Tables (1-2) (775) | Full Article (PDF)-10938K (393) | Audio-663K (7) | Peer-Review Report-201K (173) | Answering Reviewers-892K (140) | Supplementary Material-118K (138) | Received: 05/19/2021 | Revised: 07/05/2021 | Accepted: 09/16/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (9) | Total Visits (10067) | Similar Articles (66) | Timeline of Article Publication (7) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Survivin-positive circulating tumor cells as a marker for metastasis of hepatocellular carcinoma

Jing Yu, Zhan Wang, Hua Zhang, Yi Wang, Dong-Qing Li

World J Gastroenterol 27(43):7546-7562. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7546

Abstract (807) | Core Tip (687) | Article Highlights (743) | Full Article (HTML) (2786) | Figures (1-10) (595) | Tables (1-1) (367) | Full Article (PDF)-20772K (335) | Audio-1027K (8) | Peer-Review Report-205K (113) | Answering Reviewers-2134K (129) | Supplementary Material-115K (141) | Received: 05/23/2021 | Revised: 07/19/2021 | Accepted: 10/27/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (11) | Total Visits (11031) | Similar Articles (1871) | Timeline of Article Publication (0) | Authors Evaluation (2) | Article Quality Tracking (2) | What about the content of this article? (0) | Cite |

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Prospective Study

Immunoglobulin G in non-alcoholic steatohepatitis predicts clinical outcome: A prospective multi-centre cohort study

Marianne Anastasia De Roza, Mehul Lamba, George Boon-Bee Goh, Johnathan Huey-Ming Lum, Mark Chang-Chuen Cheah, Jing Hieng Jeffrey Ngu

World J Gastroenterol 27(43):7563-7571. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7563

Abstract (914) | Core Tip (757) | Article Highlights (1166) | Full Article (HTML) (2685) | Figures (1-2) (447) | Tables (1-2) (398) | Full Article (PDF)-915K (333) | Audio-1547K (8) | Peer-Review Report-144K (111) | Answering Reviewers-119K (99) | Received: 04/19/2021 | Revised: 07/20/2021 | Accepted: 11/03/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (12) | Total Visits (9860) | Similar Articles (48) | Timeline of Article Publication (3) | Authors Evaluation (1) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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Systematic Reviews

Minimum sample size estimates for trials in inflammatory bowel disease: A systematic review of a support resource

Morris Gordon, Svetlana Lakunina, Vasiliki Sinopoulou, Anthony Akobeng

World J Gastroenterol 27(43):7572-7581. Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7572

Abstract (1130) | Core Tip (938) | Article Highlights (767) | Full Article (HTML) (2369) | Figures (1-1) (396) | Tables (1-2) (854) | Full Article (PDF)-891K (324) | Audio-689K (3) | Peer-Review Report-242K (105) | Answering Reviewers-91K (125) | Supplementary Material-136K (140) | Received: 03/04/2021 | Revised: 06/30/2021 | Accepted: 10/31/2021 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Times Cited (13) | Total Visits (10017) | Similar Articles (609) | Timeline of Article Publication (0) | Article Quality Tracking (1) | What about the content of this article? (0) | Cite |

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